9 efeitos da acetilcisteína comprovados: xarope de tosse pode transformar a circulação e o coração?

1 - Become a channel member:    / @drantoniocascelli   2 - Continue learning with us (Books, Anti-Thrombosis Protocol, E-books and much more): https://antoniocascelli.com/vitrine/ 3 - Support our social projects (Antonio Cascelli Institute) PIX - CNPJ: 62.721.364/0001-18 N-acetylcysteine ​​(NAC) is a derivative of the amino acid L-cysteine ​​that functions as a direct precursor to glutathione, the most potent endogenous antioxidant in the human body. NAC provides the cysteine ​​necessary for the synthesis of reduced glutathione, allowing the body to maintain robust antioxidant defenses against cellular oxidative stress. The mechanism of action of NAC is multifactorial. It increases intracellular glutathione synthesis, allowing for the neutralization of free radicals, reduction of oxidative stress, and protection of critical cellular structures. NAC binds heavy metals such as aluminum, lead, mercury, and cadmium, preventing their absorption and facilitating their elimination. It also exerts a mucolytic effect, reducing the viscosity of respiratory secretions. Furthermore, it modulates the inflammatory response by reducing pro-inflammatory cytokines such as TNF-alpha and IL-6. In the liver, NAC demonstrates efficacy in non-alcoholic fatty liver disease (NAFLD). Studies show that NAC reduces hepatic fat accumulation, particularly in moderate degrees (grade 2), by reducing oxidative stress and hepatic inflammation. Association with betaine and spirulina potentiates the effect, as betaine modulates lipid metabolism and spirulina provides hepatoprotective nutrients. In the lungs, NAC has been used for decades in the treatment of cystic fibrosis and chronic obstructive pulmonary disease (COPD). It reduces mucus viscosity and reduces respiratory exacerbations. In psychiatry, recent studies demonstrate a significant effect on obsessive-compulsive disorder (OCD). Meta-analysis of clinical trials showed that NAC at doses of 2,400-3,000 mg daily reduced OCD symptoms by 35-45%, with a significant reduction after 12 weeks of continuous use. Therapeutic doses range from 600-1,200 mg daily for preventive use, up to 2,400-4,800 mg daily for the treatment of behavioral disorders under medical supervision. Fluimucil, a popular commercial form containing NAC, often contains sweeteners such as saccharin or sucrose, making it unsuitable for chronic supplementation. For prolonged use, pure NAC in capsules or powder without additives is preferable. About Dr. Antonio Cascelli Master's and PhD from SCMBH-MEC Specialist in: Vascular Surgery, Angiology, Angioradiology and Endovascular Surgery