Does Bulking and Cutting Actually Do Anything?
The oldest argument in lifting. Bulk to 200, cut to 180, are you back where you started? We lay out what sets the muscle-to-fat ratio of a gain, why 'lose it later' fights the evidence, and a health-first way to choose your direction. Chapters: 0:00 What decides muscle vs fat when you gain 2:29 Health first: should you lose fat first? 6:25 The 'lose it later' myth and how to do it right Resources Barbell Medicine coaching and templates: https://www.barbellmedicine.com https://www.barbellmedicine.com/shop/... https://www.barbellmedicine.com/shop/... Signal book pre-order: https://www.barbellmedicine.com/shop/... Enhanced Games results, AP News, 25 May 2026. https://apnews.com/article/enhanced-g... Bhasin S, et al. Supraphysiologic testosterone and muscle size and strength. N Engl J Med. 1996. https://pubmed.ncbi.nlm.nih.gov/8637535/ Warrier AA, et al. Performance-enhancing drugs in healthy athletes: an umbrella review. Sports Health. 2024. https://pubmed.ncbi.nlm.nih.gov/37688... ACSM. Resistance Training Prescription... An Overview of Reviews. Med Sci Sports Exerc. 2026. https://acsm.org/resistance-training-... Morton RW, et al. Neither load nor systemic hormones determine RT hypertrophy or strength in trained men. J Appl Physiol. 2016. https://pubmed.ncbi.nlm.nih.gov/27174... Vieira AF, et al. Failure vs not to failure for strength, hypertrophy, power: meta-analysis. J Strength Cond Res. 2021. https://pubmed.ncbi.nlm.nih.gov/33555... Refalo MC, et al. Proximity-to-failure and hypertrophy: meta-analysis. Sports Med. 2023. https://doi.org/10.1007/s40279-022-01... Borde R, et al. Dose-response of resistance training in healthy old adults: meta-analysis. Sports Med. 2015. https://pubmed.ncbi.nlm.nih.gov/26420... Cadore EL, et al. Sets to failure vs not in elderly men: randomized trial. Exp Gerontol. 2018. https://pubmed.ncbi.nlm.nih.gov/29577... Helms ER, et al. Small vs large energy surplus in resistance-trained individuals. Sports Med Open. 2023. https://link.springer.com/article/10.... Longland TM, et al. Higher protein during energy deficit with intense exercise. Am J Clin Nutr. 2016. https://pubmed.ncbi.nlm.nih.gov/26817... STEP 1 body-composition substudy (semaglutide). J Endocr Soc. 2021. https://academic.oup.com/jes/article/... SURMOUNT-1 body-composition substudy (tirzepatide). Diabetes Obes Metab. 2025. https://dom-pubs.onlinelibrary.wiley.... Forbes SC, et al. Creatine and resistance training on lean tissue and strength in older adults: meta-analysis. Nutrients. 2021. https://www.ncbi.nlm.nih.gov/pmc/arti... Ding P, et al. GLP-1 receptor agonists and risk of paralytic ileus: Mendelian randomization. medRxiv 2024 (preprint, not peer reviewed). https://doi.org/10.1101/2024.10.17.24... Pelland JC, et al. Resistance training dose response: volume and frequency meta-regressions. Sports Med. 2026. https://pubmed.ncbi.nlm.nih.gov/41343... Schoenfeld BJ. Mechanisms of muscle hypertrophy. J Strength Cond Res. 2010. https://pubmed.ncbi.nlm.nih.gov/20847... Nuell S, et al. Hamstring muscle volume and sprint performance. J Strength Cond Res. 2021. https://pubmed.ncbi.nlm.nih.gov/33555... Sanchis-Moysi J, et al. Muscle hypertrophy in prepubescent tennis players (MRI). PLoS One. 2012. https://pubmed.ncbi.nlm.nih.gov/22428... Wang R, et al. Variable-resistance vs constant-resistance training and maximum strength: meta-analysis. IJERPH. 2022. https://pmc.ncbi.nlm.nih.gov/articles... Retraction notice, Soria-Gila MA, et al. Variable resistance training on maximal strength. J Strength Cond Res. 2018. https://pubmed.ncbi.nlm.nih.gov/30540... Haugen ME, et al. Free-weight vs machine-based training: meta-analysis. BMC Sports Sci Med Rehabil. 2023. https://pubmed.ncbi.nlm.nih.gov/37582... Aune D, et al. Fruit and vegetable intake and mortality: dose-response meta-analysis. Int J Epidemiol. 2017. https://doi.org/10.1093/ije/dyw319 Ding EL, et al. SHBG and risk of type 2 diabetes. N Engl J Med. 2009. https://www.nejm.org/doi/full/10.1056... Vermeulen A, et al. Estimation of free testosterone in serum. J Clin Endocrinol Metab. 1999. https://academic.oup.com/jcem/article... Bhasin S, et al. Testosterone therapy in men with hypogonadism: Endocrine Society guideline. J Clin Endocrinol Metab. 2018. https://academic.oup.com/jcem/article... Coleman KJ, et al. Initial validation of an exercise vital sign in EMRs. Med Sci Sports Exerc. 2012. https://pubmed.ncbi.nlm.nih.gov/22688... Sallis JF, et al. Physical activity assessment, prescription and referral in US healthcare (It's Time to Move). Prog Cardiovasc Dis. 2021. https://pubmed.ncbi.nlm.nih.gov/33383...

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