Pigments - Part 1

When examining histological sections we sometimes come across pigmented material of yellow, brown or black appearance, which is entirely unrelated to the dyes applied during staining. Sometimes these pigments are just artefacts caused by tissue handling in the laboratory, but other times they may provide vital diagnostic information. In this first of two videos, I demonstrate some of the types of pigments commonly observed in tissue sections and discuss how solubility tests and bleaching protocols can be used to determine their identity and clinical significance.