Colloque HUG ¦ Lymphome T cutané - Dre Begonia Cortes Sanchez

This presentation explores cutaneous T-cell lymphomas, with a focus on mycosis fungoides and Sézary syndrome, their diagnostic challenges, and recent therapeutic advances. Through a clinical case, this lecture addresses the pathophysiology, diagnostic criteria, current and innovative treatments, as well as the role of allogeneic transplantation and new immunotherapies in advanced stages. Chapters: 00:00 Introduction and initial clinical case 00:27 Clinical presentation of mycosis fungoides 01:53 Definition and epidemiology of cutaneous T-cell lymphomas 02:18 Clinical manifestations and variants of mycosis fungoides 04:38 Sézary syndrome: diagnosis and blood involvement 05:26 Pathophysiology and tumor microenvironment 06:54 Staging, prognosis, and progression factors 08:49 Treatments of early stages and chlormethine gel 12:02 Immunotherapies, allogeneic transplantation, and new molecules 22:08 Diagnostic pitfalls and the link between dupilumab and lymphoma #CutaneousLymphoma #MycosisFongoides #SézarySyndrome #Dermatology #Hematology #Immunotherapy #Oncology #Dermatopathology #Dupilumab #Medicine