Advances in Management of ADPKD: A Comprehensive Approach - BC Kidney Days 2019

Dr. Fouad Chebib presents his talk, “Advances in ADPD management: a comprehensive approach,” as part of BC Kidney Days 2019. 0:02:54 – Diagnosis and Prognosis He begins by talking about the difficulties of diagnosing ADPKD, for example when GFR levels appear to be normal. He talks about historical milestones when advances in treating ADPKD occurred. Dr. Chebib discusses diagnosing ADPKD in families and provides a case example; a poll from the audience is taken on which family members in the case example should be further tested – and the answer is surprising. He provides details on when testing is truly needed. 0:29:30 – Management of ADPKD Dr. Chebib talks about the pathophysiology of ADPKD, and the rationale for using Vasopressin receptor (V2) antagonists such as Tolvaptan for treatment. He highlights data from the TEMPO trial and talks about the best ways to prescribe Tolvaptan and manage ADPKD. He emphasizes the importance of starting Tolvaptan before patients reach stage three kidney disease, to delay the need for dialysis. 0:46:55 – Questions from the Audience #PolycysticKidneyDisease #KindeyCare

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