Trombofilia: quando farla e quando no — congresso con il Prof. Dentali

I attended a conference on thrombophilia at the ASST Valle Olona in Busto Arsizio. On stage were Professor Francesco Dentali, one of the world's leading experts on the topic, and Dr. Nicola Mumoli, director of the Cardiovascular Department. The central message is uncomfortable but crystal clear: in the vast majority of cases, thrombophilia screening should not be done. Why? Because there are no randomized controlled trials demonstrating that doing so actually changes clinical outcomes. Zero. None. In the video, Professor Dentali explains: Which thrombophilias have a real impact and which do not Why, to avoid a single death, 20,000 women should be screened before prescribing the pill When thrombophilia should be measured and when it is contraindicated (pregnancy, anticoagulant therapy, acute episode) The problem of false positives and "imaginary diseases" created by excessive screening The role of antiphospholipid antibodies and antiphospholipid syndrome Why homocysteine ​​and the MTHFR mutation should almost never be measured High-level technical content, designed for physicians, gynecologists, internists, and cardiologists. Not theory: clinical practice, real data, and comparative guidelines. Are you a physician? Tell us in the comments how you manage thrombophilia in your daily practice. Subscribe to the Alberto Molteni MD channel for serious content on medicine, surgery, and Italian healthcare. 00:00 Introduction and presenters 01:56 Prof. Dentali: The spirit of the conference — reducing thrombophilia 04:49 History and classification of thrombophilias 09:00 Thrombophilia and risk of recurrence: what the literature says 13:40 When to do and when not to do thrombophilia testing 19:04 Zero RCTs: the missing evidence 21:00 Thrombophilia and estrogen-progestin therapy: 20,000 screens for 1 death 25:36 When NOT to measure thrombophilias 32:30 Thrombophilia and pregnancy: risks and prophylaxis 43:06 Randomized trial: heparin vs. nothing in pregnancy 44:53 Recurrent miscarriage and thrombophilia 46:32 Antiphospholipid antibodies: new definition 51:11 MTHFR and homocysteine: almost never useful 54:19 Discussion and questions from the room ✅ SUBSCRIBE TO THE CHANNEL AND FOLLOW ME ON SOCIAL MEDIA! Instagram: @albertomoltenimd TikTok: https://www.tiktok.com/@albertomolten... Facebook:   / albertomoltenimd   Telegram Channel: https://t.me/albmoltenimd #thrombophilia #emergencymedicine #albertomoltenimd #doctors #italianhealth