Choosing the Right Progesterone Prescription, With Dr. Felice Gersh, MD | The DUTCH Test

In this episode, ‪@FeliceGershMD‬ joins host Dr. Jaclyn Smeaton and DUTCH founder Mark Newman for a deep-dive on progesterone: its physiological roles, concerns around standard-of-care prescribing practices, and more. Their conversation also explores: Progesterone’s role as more than an endometrial protectant Supraphysiologic allopregnanolone created by oral micronized progesterone The physiological benefits of cyclic dosing versus continuous dosing How the gut microbiome impacts progesterone metabolism The need for more research on oral micronized progesterone and dosing methods Show Notes Learn more about Dr. Gersh’s practice Integrative Medical Group of Irvine (https://integrativemgi.com/) and her books (https://integrativemgi.com/about-dr-f...! Read Dr. Smeaton’s article on oral micronized progesterone in menopause (https://dutchtest.com/articles/oral-m.... Become a DUTCH Provider to get access to comprehensive patient reports, peer-reviewed and validated research, and expert clinical support. https://dutchtest.com/for-providers Key Moments 0:50 Episode Introduction 3:51 Dr. Felice Gersh's Unique Medical Journey 13:42 The Importance of Progesterone in Women's Health 18:45 Biochemistry of Progesterone and Its Metabolites 23:48 Natural vs. Synthetic Hormones: Understanding the Differences 29:05 The Role of Micronized Progesterone in Therapy 31:39 Become A DUTCH Provider 32:19 Concerns and Considerations in Hormone Therapy 40:30 Exploring Hormonal Pathways and Metabolism 46:22 Cyclic vs Continuous Hormone Therapy 54:33 Vaginal Progesterone: Efficacy and Alternatives 1:00:17 Monitoring Hormone Levels and Clinical Implications