Anne Gaucher | Understanding and rationalizing cooperativity effects between non- covalent

Anne Gaucher, Université Paris-Saclay, France Title: Understanding and rationalizing cooperativity effects between non- covalent interactions: towards more efficient anion receptor platforms Abstract: Anions play a crucial role in various fields, including biology, medicine, catalysis and environmental sciences. Consequently, the design of new anion receptors has become an important challenge in modern organic chemistry. We have designed new anion receptors based on the combination of two types of fragments: a urea derivative capable of generating hydrogen bonds and and a π-deficient heterocycle capable of generating anion- interactions. The design of these anion receptors is essential because non-covalent interactions individually contribute to the structuring and properties of complex three-dimensional molecular assemblies. When combined within a single multifunctional molecular platform, they can generate cooperative, non-cooperative or anti- cooperative phenomena. The combination of molecular modelling and analytical chemistry will be presented to provide some understanding of such complex effects. Biography: Anne Gaucher studied chemistry at the University of Paris-Sud where she obtained her Ph.D in 1992 working on Amino Cyclopropane Carboxylic acids (ACCs) with Dr. J. Salaün. After a postdoctoral period at the University of Texas in Austin (USA) with Professor S. F. Martin, working on the total synthesis of breynolide, she obtained a one year teaching position at the University of Paris-Sud and then a permanent one at the University of Versailles St Quentin. Her research mainly focuses on the design, synthesis, properties of polyfunctionalized molecules and the study of weak interactions. #WCCE2026 #chemistry #chemistryconferences #catalysis #analyticalchemistry #organicchemistry #greenchemistry #nanotechnology #environmentalchemistry #inorganicchemistry #organometallics #materialscience #syntheticchemistry #biochemistry #greenchemistry #medicinalchemistry #chemicalresearch #chemicalengineering