L-04 GPCR Signaling Complete Lecture Part 2 | Biochemistry for CSIR NET & NEET

📚 Welcome to Part 2 of the GPCR (G Protein-Coupled Receptor) Signaling Series! In this lecture, Dr. Mukesh Sir (Ph.D., AIIMS) explains two of the most important topics in cell signaling—GPCR receptor desensitization and Nitric Oxide (NO) signaling. These concepts are frequently tested in CSIR NET, GATE Biotechnology, DBT BET, CUET PG, NEET PG, MBBS, MSc, and other Life Science examinations. This lecture is designed to simplify complex signaling pathways using clear diagrams, step-by-step explanations, and high-yield concepts. 📖 Topics Covered ✅ GPCR Receptor Desensitization ✅ Homologous vs Heterologous Desensitization ✅ GRKs (G Protein-Coupled Receptor Kinases) ✅ β-Arrestin-Mediated Desensitization ✅ Receptor Internalization ✅ Receptor Recycling & Downregulation ✅ Nitric Oxide (NO) Signaling ✅ Nitric Oxide Synthase (NOS) ✅ eNOS, nNOS & iNOS ✅ Soluble Guanylyl Cyclase (sGC) ✅ cGMP Signaling ✅ Protein Kinase G (PKG) ✅ Physiological Functions of NO ✅ Vasodilation ✅ Clinical Significance of Nitric Oxide ✅ High-Yield MCQs & Previous Year Questions 🎯 This Lecture is Useful For CSIR NET Life Science GATE Biotechnology (BT) DBT BET IIT JAM Biotechnology CUET PG NEET PG MBBS MSc Biochemistry Biotechnology Molecular Biology Medical Biochemistry Pharmacy BSc & MSc Life Sciences 📚 Cell Signaling Playlist If you're preparing for competitive exams, watch the complete Cell Signaling series covering: ✔ GPCR Signaling (Part 1 & Part 2) ✔ RTK Signaling ✔ PI3K-AKT-mTOR Pathway ✔ Non-Receptor Tyrosine Kinases ✔ JAK-STAT Pathway ✔ TGF-β Signaling ✔ Wnt Signaling ✔ Hedgehog Pathway ✔ Notch Signaling ✔ MAPK/ERK Pathway 👍 Support the Channel If you found this lecture helpful: ✅ Like the video ✅ Share it with your friends ✅ Subscribe for more Biochemistry & Life Science lectures ✅ Press the Bell Icon 🔔 to never miss an update GPCR signaling, GPCR Part 2, receptor desensitization, receptor internalization, β-arrestin, GRK, nitric oxide signaling, NO signaling pathway, cGMP pathway, guanylyl cyclase, PKG signaling, eNOS, iNOS, nNOS, cell signaling, signal transduction, biochemistry, molecular biology, CSIR NET Life Science, GATE Biotechnology, NEET PG, MBBS biochemistry, biotechnology lecture, Dr Mukesh Sir, AIIMS. Hashtags #GPCR #CellSignaling #NitricOxide #NOSignaling #ReceptorDesensitization #SignalTransduction #Biochemistry #CSIRNET #GATEBT #NEETPG #MBBS #LifeScience #Biotechnology #MolecularBiology #DrMukeshSir #AIIMS #HighYield #biochemistrylecture #drmukeshmamgain