L-03 Cholera Toxin & Pertussis Toxin Explained | G Protein Signalling Made Easy

Cholera Toxin & Pertussis Toxin Explained | G Protein Signalling Made Easy These bacterial toxins are among the most frequently asked topics in CSIR NET, GATE Biotechnology, DBT BET, ICMR JRF, CUET (PG), M.Sc. Entrance, NEET-UG, and University Exams. In this lecture, you'll understand how Cholera toxin and Pertussis toxin alter GPCR signalling through G proteins (Gs and Gi) with simple diagrams and easy-to-remember concepts. 📚 Topics Covered ✅ Introduction to Cholera & Pertussis Toxins ✅ Vibrio cholerae and Bordetella pertussis ✅ GPCR Signalling Recap ✅ Heterotrimeric G Proteins (Gs & Gi) ✅ ADP-Ribosylation Mechanism ✅ Cholera Toxin Mechanism (Gs Activation) ✅ Pertussis Toxin Mechanism (Gi Inhibition) ✅ Adenylyl Cyclase Regulation ✅ cAMP Production & Protein Kinase A (PKA) ✅ Cellular Effects of Increased & Decreased cAMP ✅ Fluid Secretion & Cholera Pathogenesis ✅ Clinical Importance & Exam-Oriented MCQs ✅ Memory Tricks for Competitive Exams 🎯 Perfect For CSIR NET Life Science GATE Biotechnology DBT BET ICMR JRF CUET (PG) M.Sc. Biotechnology & Life Sciences NEET-UG B.Sc. & M.Sc. Students Medical & Paramedical Students 📚 Explore More Playlists 🧬 Cell Communication & Signalling | From Basics to Advanced    • Cell Communication & Signalling | From Bas...   🧪 Biochemistry    • Biochemistry Complete Course | Biomolecule...   🦁 Animal Kingdom    • Complete Zoology: Animal Kingdom   💡 By the end of this lecture, you'll clearly understand why Cholera toxin persistently activates Gs proteins, why Pertussis toxin inhibits Gi proteins, and how both toxins affect intracellular cAMP levels—a favorite topic in competitive exams. 👍 If you enjoyed the lecture, don't forget to Like 👍, Share 📤, Comment 💬, and Subscribe 🔔 for more Biology lectures every week! #CholeraToxin #PertussisToxin #GPCR #GProtein #GsProtein #GiProtein #CellSignalling #SignalTransduction #Biology #Biochemistry #CSIRNET #NEET #CUET #GATEBT #DBTBET #LifeScience #Biotechnology #MolecularBiology #MedicalBiochemistry #BiologyLecture #drmukeshmamgain