How to use Mounjaro (tirzepatide) - Injection Demonstration

Mounjaro is used to manage blood sugar in people 10 years and older with type 2 diabetes, together with diet and exercise. It’s available as single-dose pens (also called an autoinjector), single-dose vials, multi-dose vials, and a KwikPen. It comes in six different doses, and is injected once a week under the skin. Mounjaro is a GIP and GLP-1 receptor agonist. If you have been prescribed Mounjaro, the brand name for tirzepatide, you should have received training from your healthcare professional on how to give yourself the injection safely. In this video, we will review step-by–step how to give yourself a Mounjaro injection using the pre-filled single-dose pen. Before using Mounjaro, review the Instructions for Use provided with your prescription. When you are ready to inject your dose, gather your materials. You will need: Your Mounjaro pen, a piece of gauze or a cotton ball, an alcohol swab, and a sharps container. Now that you are ready to inject your dose, let’s review the steps on how to inject your Mounjaro single-dose pen. — Step One: Check your pen to make sure the medication isn’t expired, frozen, or cloudy. It should look colorless to slightly yellow, and shouldn’t have particles in it. — Step two: Wash your hands with soap and water. — Step three: Choose your injection site. If you are injecting Mounjaro by yourself, you can inject it into your stomach, 2 inches away from your belly button, or into your thigh. If someone else is helping you, they can inject it into the back of your upper arm. Make sure to change your injection site each week. Clean your chosen injection site with an alcohol swab. — Step four: While the pen is locked, pull off the gray base cap and throw it away. — Step five: Place the clear base flat against your skin at the injection site, then twist the top of the pen to the “unlocked” position. — Step six: While holding the pen firmly against your skin, press and hold the purple injection button for up to 10 seconds. You will hear a click signaling the injection has started, and a second loud click when the injection is completed. The injection is done when you can see the gray plunger. — Step seven: Remove the pen from your skin and place it directly into a sharps container. — Step eight: If you have any bleeding at the injection site, you can press a cotton ball or gauze over the injection site until the bleeding has stopped. If you have any questions about how to inject Mounjaro, contact your healthcare provider or the manufacturer, Lilly. References: 1. Mounjaro [package insert]. Updated January 2026. Eli Lilly and Company. Accessed February 26, 2026 at https://dailymed.nlm.nih.gov/dailymed... —— Follow Drugs.com: Facebook:   / drugscom   Twitter (X):   / drugscom   Instagram:   / drugs.com_official   TikTok:   / drugs.com_official   Pinterest:   / drugscom   Subscribe to our newsletter: https://www.drugs.com/newsletters/ —— About Drugs.com: Drugs.com is the most popular, comprehensive and up-to-date source of drug information online. Providing free, peer-reviewed, accurate and independent data on more than 24,000 prescription drugs, over-the-counter medicines & natural products. Find helpful tools, wallet size personal medication records, mobile applications and more.