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Online and in-person consultations → https://ua.ultraclinic.com.ua/ua/price Individualized support → https://ua.ultraclinic.com.ua/ua/gp-p... ------------------------------------------------------------------------------------ Course: "How to slow down the aging process." Practical Guide" https://www.udemy.com/course/romikwvf... Course "How to Reprogram Your Body and Get Slim Forever" https://www.udemy.com/course/bxbphbez... Course "Treating Hypertension Without Drugs" https://www.udemy.com/course/vhqksohh... Course "Learn to Lower Cholesterol Without Drugs (How to Overcome Atherosclerosis)" https://www.udemy.com/course/nkbfkzcj... --------------------------------------------------------------------------------------- Timecodes: 00:00 What is mitochondrial therapy 01:19 Why you can't just "replace mitochondria" 01:57 Fatigue is not an indication for mitochondrial therapy 03:17 Where mitochondrial therapy has already become medicine 03:31 TK2 deficiency and the drug KYGEVVI 04:45 Barth syndrome and elamipretide 05:33 LHON: Leber's hereditary optic neuropathy 06:32 Why success with one disease can't be generalized to everyone 07:16 Mitochondrial donation, gene therapy, and experimental Methods 08:14 What the average person can actually do 09:19 Supplements are a secondary concern 09:57 "Mitochondrial cocktails" and CoQ10 11:03 NAD boosters, NMN, NR, MitoQ, urolithin A 11:38 A biomarker is not a patient 12:31 Safety: Drugs and mitochondrial diseases 13:25 How to read new research on mitochondria 14:13 Key takeaway: Don't label yourself as having "mitochondrial dysfunction" 14:46 Summary: Diagnosis, mechanism, benefits, risks ---------------------------------------------------------------------------------------------------------- Sources: 1. FDA — KYGEVVI: thymidine kinase 2 deficiency https://www.fda.gov/drugs/news-events... 2. EMA - Kygevvi https://www.ema.europa.eu/en/medicine... 3. FDA - FORZINITY / elamipretide for Barth syndrome https://www.fda.gov/news-events/press... 4. EMA – Raxone / idebenone for LHON https://www.ema.europa.eu/en/medicine... 5. Klopstock T. et al. Idebenone in Leber’s hereditary optic neuropathy. Brain, 2011 https://pubmed.ncbi.nlm.nih.gov/21788... 6. Karaa A. et al. Elamipretide in primary mitochondrial myopathy: MMPOWER-3. Neurology, 2023 https://pubmed.ncbi.nlm.nih.gov/37268... 7. HFEA - Mitochondrial donation treatment https://www.hfea.gov.uk/treatments/em... 8. Mitochondrial Donation and Preimplantation Genetic Testing for mtDNA Disease. NEJM, 2025 https://www.nejm.org/doi/full/10.1056... 9. Mitochondrial Medicine Therapies: rationale, evidence, dosing guidelines https://pmc.ncbi.nlm.nih.gov/articles... 10. Cochrane - Treatment for mitochondrial disorders https://www.cochrane.org/evidence/CD0... 11. Urolithin A supplementation, muscle endurance and mitochondrial health. JAMA Network Open, 2022 https://jamanetwork.com/journals/jama... 12. Safety of drug use in patients with primary mitochondrial disease: international Delphi consensus https://pmc.ncbi.nlm.nih.gov/articles...

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