The Secret Behind a Strange Stimulant
This is an investigation into why 8-chlorotheophylline is present as a stimulant in Gravol anti-nausea medication. A huge thanks to tay and yuyuhakase from the Discord! Support the Channel on Patreon - / thatchemist Join the Community Discord! - / discord Second Discord link if the first one is borked - / discord ---------------------------------------------------------------------------------------------------------------------------------- References: 1st patent - https://patents.google.com/patent/US2... 2nd patent - https://patents.google.com/patent/US2... 1st science paper - https://www.doi.org/10.1126/science.1... 2nd science paper - https://www.doi.org/10.1126/science.1... anti-nausea discovery - https://www.doi.org/10.1126/science.1... Predicted pKa sources: 8-chlorotheophyline - https://www.chemicalbook.com/ProductC... theophylline - https://pubchem.ncbi.nlm.nih.gov/comp... diphenhydramine - https://pubchem.ncbi.nlm.nih.gov/comp... ---------------------------------------------------------------------------------------------------------------------------------- I made this thumbnail with DOLL-E
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