Zepbound Dosing: Your Doctor Probably Didn't Tell You About This Issue

Voafit is now the official sponsor of the On The Pen Podcast, learn more here: https://www.Voafit.com/otp Are you on tirzepatide or semaglutide and struggled with inconsistent weight loss and side effects? On this episode of On The Pen, Dave Knapp and Dr. Ian Ellis dive into the surprising variability of GLP-1 dosing (retatrutide, tirzepatide), even when the weekly dose remains the same. We explore how these subtle dosage changes can lead to frustrating glp-1 side effects and why many individuals eventually give up on their weight loss medication. This new way of thinking about glp-1 dosing could change the obesity medicine game. Referenced Links: http://www.OTPLinks.com 00:00 Why most GLP-1 users are never on the same dose twice 01:55 Dr. Ian's background: trainer, nutritionist, ER physician 04:00 His obsessive relationship with food and body composition 07:45 The two impossible choices: obsession or obesity 10:12 How medical school destroyed his health 10:25 A colleague mentions Ozempic for the first time 11:35 His first dose and what real satiety feels like 13:00 Why the same dose felt worse every single week 15:00 30 lbs lost but the body scan results were horrifying 17:30 Why elderly patients are especially at risk on GLP-1s 18:35 Patient case: Pat May, 310 lbs, lost over 100 lbs 20:45 Semaglutide half-life and dose stacking explained 24:50 The therapeutic window and finding your ideal level 26:30 Why the dosing protocol was built for trials not people 28:00 You are never on the same drug level twice 29:00 Patient case: Mary Alice lost 30 lbs below the starting dose 32:00 The math behind calculating your precise GLP-1 level 35:00 The VoaFit app and making precision dosing scalable 36:00 Their patients lost more weight using half the medicine 39:30 Why 40 to 70 percent of people quit GLP-1s 42:00 Compounding pharmacies and the case for flexible dosing 46:00 Using GLP-1 as a thermostat dial for your appetite 56:45 Where precision dosing is available now 58:30 Beyond GLP-1s: applying this to testosterone and more 1:05:30 Why hitting the dose ceiling kills long-term results 1:07:00 Dr. Ian's outcome: off GLP-1s completely 1:10:00 Fixing a broken one-size-fits-all dosing paradigm 1:13:00 How to find Dr. Ian Ellis and VoaFit