Perimenopause 101: The Basics

For too long, perimenopause has been treated as a mystery—or worse, dismissed as "just part of getting older." But understanding what is happening to your body in this chaotic chapter changes everything. In this episode, Dr Claudia Gray and Christy Herselman finally turn the spotlight on themselves and every woman navigating this hormonal rollercoaster. They start with the basics: what is the difference between perimenopause and menopause, and why does it matter? Claudia explains that menopause is a single point in time—twelve months without a period—while perimenopause is the years leading up to it, when your ovaries start getting lazy and your hormones become wildly unpredictable. This phase can begin in your late thirties, last up to a decade, and leave women feeling like they are losing their minds. But here is the truth: you are not losing your mind. Your estrogen is fluctuating. And estrogen, as it turns out, is not just about reproduction. Estrogen receptors are found in your muscles, your bones, your fat tissue, your liver, your pancreas, and crucially, your brain. So when estrogen drops, everything changes. The irritability, the brain fog, the joint pain, the thinning hair, the middle-aged spread, the sleeplessness, the night sweats that arrive late in the process—all of it makes sense once you understand the whole body picture. But beyond the day-to-day symptoms, Claudia highlights the serious health risks that come with declining estrogen: increased cardiovascular risk, bone density loss, muscle mass reduction, unfavourable cholesterol changes, and higher risks of certain cancers. Perimenopause, she argues, is a whole body shift with real medical consequences—and women need to know this so they can act. If you have been feeling unlike yourself, struggling to cope with what you used to handle easily, or wondering why everything feels harder than it should, this episode is your starting point. Knowledge is power. And this conversation is the first step toward taking back some control. Dr Claudia Gray: Instagram:   / dr_claudia_gray   Dr Claudia Gray’s Real Parenting and Paediatrics, Quivertree Publications 2025 https://www.takealot.com/dr-gray-s-re... Christy Herselman: Instagram:   / thechatdurban   Books: https://thechat.co.za/product-categor...