Why 4 Drugs Work Better in Myeloma: Quadruplet Therapy Explained | Myeloma Made Simple

Should myeloma patients start with 2, 3, or 4 drugs? In this Myeloma Made Simple episode, Dr. Joseph Mikhael breaks down why quadruplet therapy (4 drug combination therapy) is now the new standard of care for treating newly diagnosed multiple myeloma patients. Learn what these four drugs are, how they work together, and what major studies like PERSEUS, CEPHEUS, and IMROZ revealed. This is your simple, patient-friendly guide to deeper, longer-lasting remission in the frontline setting. Topics covered in this video: 0:00 — Intro 1:02 — What are quadruplets in myeloma treatment? 1:14 — Why frontline therapy changed in the past year 2:14 — What drugs make up the quadruplet? 3:27 — Key clinical trials: PERSEUS, CEPHEUS & IMROZ 3:50 — What the trials proved: 4 drugs are better than 3 drugs 4:07 — Why the first remission matters most 4:53 — Recap: The new standard of care for myeloma Subscribe for weekly updates on myeloma research, treatment, and patient support. Have a question that needs more personalized support? Call us! We’re here for you. The IMF’s InfoLine is available to answer your myeloma-related questions and concerns. Call us at 1-818-487-7455, email us at [email protected], or schedule your call at a time that works best for you at: https://www.myeloma.org/infoline. Supported by an educational grant from Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC _______________ Improving Lives | Finding the Cure Founded in 1990, the International Myeloma Foundation (IMF) is the first and largest organization focusing specifically on multiple myeloma. The IMF’s reach extends to more than 525,000 members in 140 countries worldwide. The IMF is dedicated to improving the quality of lives of myeloma patients while working toward prevention and a cure through our four founding principles: Research, Education, Support, and Advocacy. Subscribe to our channel:    / imfmyeloma   Visit our website at: https://www.myeloma.org Find us online: Facebook: @myeloma |   / myeloma   X/Twitter: @IMFMyeloma |   / imfmyeloma   Instagram: @imfmyeloma |   / imfmyeloma   LinkedIn:   / international-myeloma-foundation   Support the IMF | Donate Now! https://fundraise.myeloma.org/give/52... Category Nonprofits & Activism License Standard YouTube License The International Myeloma Foundation is committed to accessibility for all. That’s why all English-language videos uploaded to our YouTube channel feature human-transcribed closed captioning. This ensures more accurate captions for viewers who are Deaf or hard of hearing and improves the quality of automatic translations into other languages for our global audience.