ENZIMAS. REGULACIÓN ENZIMÁTICA Activación Inhibición Alosterismo

PDF of the video: http://www.mediafire.com/view/zwkq3hk... ENZYME REGULATION For an organism, both the environment and its needs are constantly changing. This requires that its metabolic pathways and the rate at which they occur vary according to these changes. This is known as metabolic flexibility and occurs thanks to the regulation of the enzymes that catalyze physiological reactions; this is enzyme regulation. Nature has favored and continues to favor those organisms that follow the principle of maximum cellular economy, whereby only those enzymes that are necessary at any given time remain active. Thus, it is not efficient for a cell to keep its entire enzymatic package functioning when it only needs half of it, so increasingly precise mechanisms for controlling enzyme activity have progressively developed. There are three basic regulatory mechanisms. 1. ACTIVATION. Based on substances that allow enzymes to act (activators) 2. INHIBITION. The main substances in this type of regulation are inhibitors, which slow down or stop enzyme activity. a. Irreversible (poisoning). The enzyme becomes permanently useless. b. Reversible. The enzyme does not act while the inhibitor is bound, but this situation is temporary. b.1) Non-competitive. The inhibitor prevents the substrate from binding to the active site. b.2) Competitive. The inhibitor is very similar to the substrate and competes with it for binding to the active site. 3. ALLOSTERISM. Produced by allosteric enzymes, which have one or more regulatory sites in addition to the active site. Their enzyme kinetics are given by a sigmoidal curve instead of the hyperbolic curve characteristic of other enzymes. Don't forget to subscribe to the YouTube channel!!    / eficienci.  . You can also follow us on our Facebook page:   / eficiencia.red   I hope this helps you find science more interesting and, above all, easier! :) If you have any questions, feel free to comment!