Drug Induced Liver Injury - A Medicinal Chemist's Perspective

This talk provides a medicinal chemist's perspective on the current understanding of DILI mechanisms, highlight cutting-edge assay developments for a holistic assessment, and discuss strategies for predicting DILI risks. This session aims to equip medicinal chemists with working knowledge to manage DILI risks on their programs. 00:22 Introduction 02:04 Ice-breaker questions 08:27 Presentation 39:55 Q&A Presented by Anh Tran, Ph.D. Principal Scientist and Medicinal Chemistry Team Leader at Amgen with host Dennis Koester, Director of Industry Research and Relations, Drug Hunter Presented on June 6, 2024, as a Drug Hunter Flash Talk. Sign up for future sessions here: https://drughunter.com/flash-talk-ser...

#ashishmusicmafiya | Dilwo Lenhi Badal Ge Ashish Yadav Sad Song Numberbo Leni Badal | Dj Hard BasS
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#ashishmusicmafiya | Dilwo Lenhi Badal Ge Ashish Yadav Sad Song Numberbo Leni Badal | Dj Hard BasS

ICH mache die First Class PLEITE!😳💸
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ICH mache die First Class PLEITE!😳💸

The Largest Small Molecule: Manufacturing Process for Enlicitide
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The Largest Small Molecule: Manufacturing Process for Enlicitide

A Guide to Generative AI for Medicinal Chemists, ​Presented by Ashwini Ghogare, Ph.D.
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A Guide to Generative AI for Medicinal Chemists, ​Presented by Ashwini Ghogare, Ph.D.

Acute Liver Failure | Clinical Medicine
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Acute Liver Failure | Clinical Medicine

Discovery of a Small Molecule HPK1 Inhibitor for Immuno-Oncology
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Discovery of a Small Molecule HPK1 Inhibitor for Immuno-Oncology

RAS(ON) Inhibition: Overcoming Resistance and Targeting More Variants in KRAS-Mutated NSCLC
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RAS(ON) Inhibition: Overcoming Resistance and Targeting More Variants in KRAS-Mutated NSCLC

The BEST Foods to Clean Out Your Liver
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The BEST Foods to Clean Out Your Liver

Cancer breakthroughs: Does a string of advances signal turning point? • FRANCE 24 English
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Cancer breakthroughs: Does a string of advances signal turning point? • FRANCE 24 English

Fatty Liver Expert: The Toxic Ingredient Silently Filling Your Liver With Fat - Dr David Unwin
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Fatty Liver Expert: The Toxic Ingredient Silently Filling Your Liver With Fat - Dr David Unwin

Short statured people answer questions you're too afraid to ask | You Can't Ask That | Full Episode
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Short statured people answer questions you're too afraid to ask | You Can't Ask That | Full Episode

Reimagining Druggability using Chemoproteomic Platforms
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Reimagining Druggability using Chemoproteomic Platforms

I Investigated The Country Where it's Illegal To Be Fat
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I Investigated The Country Where it's Illegal To Be Fat

What do tech pioneers think about the AI revolution? - The Engineers, BBC World Service
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What do tech pioneers think about the AI revolution? - The Engineers, BBC World Service

"Using Omics in Biomedical Research" & "Data Asset Management in the Era of Collaborative Science"
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"Using Omics in Biomedical Research" & "Data Asset Management in the Era of Collaborative Science"

Proximity Labeling for Drug Discovery
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Proximity Labeling for Drug Discovery

Dose as the Ultimate MPO Endpoint
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Dose as the Ultimate MPO Endpoint

I’m a Pathologist: The "Biological Cost" of Ozempic and Mounjaro.
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I’m a Pathologist: The "Biological Cost" of Ozempic and Mounjaro.

Peptide Expert: The Cellular "Cheat Codes" That Got Banned (& What Happens Next)
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Peptide Expert: The Cellular "Cheat Codes" That Got Banned (& What Happens Next)

Diving for Pearls: Overcoming Challenges in the Metabolism of Peptide Therapeutics
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Diving for Pearls: Overcoming Challenges in the Metabolism of Peptide Therapeutics