What You Need to Know About Packing Resins at Process Scale

Learn best practices and guidelines for successfully packing different types of chromatography resins. This includes incompressible resins like CHT Ceramic Hydroxyapatite Media as well as traditional compressible resins. CHT is an easy-to-use mixed-mode media and has high specific gravity, a rapid settling rate, and sensitivity to mechanical shear. These variations from traditional compressible resins must be considered when designing CHT column-packing protocols. In general, parameters such as compression factor, settling rate, and attributes of the base matrix need to be considered when packing resins at process scale. Packing methods can be adapted to obtain simple and the most reproducible packing. Overview - Differences between compressible and incompressible resins - Slurry preparation techniques Slurry transfer methodologies Column packing guidelines Packed column evaluation and qualification testing - A word about height equivalent to a theoretical plate (HETP) Learn more at https://www.bio-rad.com/library Subscribe to the Bio-Rad channel: https://www.youtube.com/user/BioRadLi... We Are Bio-Rad. Our mission: To provide useful, high-quality products and services that advance scientific discovery and improve healthcare. At Bio-Rad, we are united behind this effort. These two objectives are the driving force behind every decision we make, from developing innovative ideas to building global solutions that help solve our customers' greatest challenges. Connect with Bio-Rad Online: Website: http://www.bio-rad.com/ LinkedIn:   / 1613226   Facebook:   / biorad   Twitter:   / bioradlifesci   Instagram: @BioRadLabs Snapchat: @BioRadLabs ©2021 Bio-Rad is a trademark of Bio-Rad Laboratories, Inc. in certain jurisdictions. All trademarks used herein are the property of their respective owner. Music used by permission granted by royalty-free license from Pond5.com