Artrosis de RODILLA - ¿Qué MEDICAMENTOS funcionan realmente y cuáles no? [Guía 2026]

In this video, updated in 2025, Dr. Liván Peña Marrero, Specialist in Orthopedics and Traumatology, PhD, Professor and Senior Researcher, with 30 years of clinical experience, explains which medications are most commonly used to treat knee osteoarthritis and which have proven to be truly effective according to the most recent scientific evidence. Based on the recommendations of the Osteoarthritis Research Society International (OARSI), the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO), and the European League Against Rheumatism, now the European Alliance of Associations for Rheumatology (EULAR). In the treatment of osteoarthritis, a distinction is made between, on the one hand, fast-acting symptom-modifying drugs (such as NSAIDs, paracetamol, duloxetine, opioids, and topical capsaicin), whose main effect is to relieve pain in the short term. On the other hand, there are SYSADOAs (Symptomatic Slow-Acting Drugs for Osteoarthritis), that is, slow-acting symptom-modifying drugs (such as glucosamine, chondroitin sulfate, type I or II collagen, and avocado and soy unsaponifiables). These not only improve symptoms gradually, but, according to recent studies and meta-analyses, have shown some protective effect on articular cartilage, which could help slow the progression of the disease. Therefore, some authors believe that SYSADOAs could eventually be recognized as true disease-modifying drugs. Discover which treatments have lost support and which continue to be recommended by international guidelines. This content is for educational purposes only and does not constitute a recommendation or promotion of commercial products. CLARIFICATION NOTE: In this video, I mention supplements such as chondroitin sulfate, glucosamine, type II collagen, and avocado and soy unsaponifiables as being among the so-called "disease-modifying antirheumatic drugs" (DMOs). It is important to clarify that, according to international guidelines (OARSI, EULAR), these products are primarily classified as symptomatic slow-acting antirheumatic drugs (SYSADOAs). However, some studies and meta-analyses have shown evidence that they may protect cartilage or slow the progression of osteoarthritis, which is why many authors consider them candidates for DMOs. In short: they are not officially recognized as DMOs, but research suggests a possible effect beyond symptomatic relief. 👀👉 If you'd like to support the development of this channel and enjoy some perks, you can become a CHANNEL MEMBER at this link:    / @livan.ortotrauma   CHAPTERS 00:00 Introduction 01:37 Oral NSAIDs 03:21 Paracetamol 03:58 Opioids 04:38 Duloxetine 05:33 Statins 06:44 Topical NSAIDs 08:12 Topical Capsaicin 09:02 Chondroitin and Glucosamine 12:50 ASU (Avocado and Soybean Oil) 13:54 Type II Collagen #KneeOsteoarthritis #OsteoarthritisTreatment #DrLivanPeñaMarrero #chondroitin #Orthopedics #Traumatology #glucosamine #duloxetine #type2collagen #OARSIGuidelines #ESCEOosteoarthritis #EULAROsteoarthritis #KneePain #LivánOrthoTrauma