Champion-AF: o começo do fim da anticoagulação crônica na fibrilação atrial? (DozeCast 229)

For years, stroke prevention in atrial fibrillation followed a relatively simple logic: identify thromboembolic risk and prescribe anticoagulation. But clinical practice has shown that the equation is more complex. Major bleeds, intracranial hemorrhages, poor adherence, frailty, recurrent falls, and socioeconomic limitations often present doctors and patients with difficult decisions. In Ep. 228 of DozeCast, host Diandro Motta welcomes cardiologist Dr. Brunna Pileggi and neurologist Dr. Gisele Sampaio to analyze in depth the Champion-AF study, which evaluates percutaneous left atrial appendage closure (LAAC) with a Watchman device as an alternative to direct oral anticoagulation in patients with atrial fibrillation. The study's main question is simple: should we continue reserving atrial appendage closure only for extreme situations, or is it time to anticipate this decision? What you will learn: 📌 The main challenges of anticoagulation in the real world: bleeding, adherence, dose adjustment, and frail patients 📌 The neurological impact of thromboembolic events and intracranial hemorrhages 📌 The pathophysiological and clinical rationale behind left atrial appendage closure 📌 How Champion-AF was designed and why it generated so much debate in the scientific community 📌 The main results involving safety, bleeding, and combined clinical outcomes 📌 The concept of early intervention before the first major bleeding event 📌 The resistance of the medical community to paradigm shifts and the role of clinical inertia 📌 Which patients can benefit most from this strategy: frail elderly patients, patients with elevated HAS-BLED, poor adherence, or a previous history of bleeding 📌 How to apply the findings of Champion-AF in office practice and shared decision-making 📌 Real clinical scenarios involving patients with recurrent falls, previous gastrointestinal bleeding, and low Medication Adherence More than discussing a study, this episode debates a potential paradigm shift: from reacting to complications to anticipating them. Who this episode is for: Cardiologists, neurologists, clinicians, electrophysiologists, residents, and professionals involved in the management of atrial fibrillation who wish to understand the possible transformations in the preventive treatment of cardioembolic stroke. 🔔 Subscribe to the channel and activate the bell so you don't miss the next episodes of DozeCast. #atrialfibrillation #AF #ChampionAF #Watchman #LAAC #atrialappendixocclusion #stroke #anticoagulation #DOAC #cardiology #neurology #electrophysiology #dozecast #podcast #evidencebasedmedicine _____________________________________________ Receive weekly didactic reviews of Cardiology on DozeNews PRIME — the lightest and fastest way to stay updated, through the link https://news.dozeporoito.com/dozecast27.