Atomic Clarity: Exploring Disordered Proteins with 1.0 GHz Precision

In this eighth video of the "Resolution In A New Dimension For Solving Challenges Of Society" series, Prof. Miquel Pons, Scientific Director of NMR Facility, University of Barcelona, shares how Ultra-High Field NMR is transforming our understanding of intrinsically disordered proteins, key players in human biology and disease. Discover how scientific curiosity, bold decisions, and advanced instrumentation are shaping the future of structural biology. ‪@UB_endirecte‬ --- The new GHz-class NMR technology* is now enabling novel research in the functional structural biology of proteins and protein complexes. A key principle in biology is: structure determines function. Our customers try to understand how molecules interact with each other and then modify their function. This is key in finding solutions against diseases like Alzheimer's, Parkinson's, cancer and Covid-19. The increased spectral resolution and sensitivity of the 1.2 GHz NMR have already enabled research teams to look more deeply at proteins and better understand the initial steps of amyloid-type protein aggregation as well as the function and structure of the Tau protein, both commonly associated with Alzheimer’s disease. With this series, we want to highlight the ground-breaking research of our customers and show how the new GHz-class NMR technology is used for finding solutions for structural biology key questions. Watch other videos of the series: https://goto.bruker.com/3JroGkq *Research use only. Bruker NMR instruments are not intended for use in clinical diagnostic procedures. #Bruker #NMR #Biology