Knorr Pyrrole Synthesis of Knorr's Pyrrole
In this video I show the Knorr pyrrole synthesis of 3,5-diethoxycarbonyl-2,4-dimethylpyrrole, also known as diethyl 3,5-dimethylpyrrole-2,4-dicarboxylate, also known as simply Knorr's pyrrole. This is a nice one pot reaction with 32.5g of ethyl acetoacetate, 75mL of glacial acetic acid, 8.7g of NaNO2, and 16.7g of zinc. / corrosion
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