Anticholinergic Drug Toxicity | Toxidrome Effects and Mechanism of Action [Pharmacology Made Easy]

Anticholinergic drug toxicity and pharmacology is made easy using this simple trick to remember the symptoms and effects of anticholinergic toxidrome. Great for nursing, medical, and USMLE! Most anticholinergic drugs are antimuscarinic (few act on nicotinic cholinergic receptors), and their mechanism of action involves blocking acetylcholine from binding to the cholinergic muscarinic receptors of the parasympathetic nervous system. Anticholinergic drug toxicity or overdose results in many sympathetic-like symptoms because the parasympathetic nervous system is blocked, leaving an unopposed sympathetic nervous system. Anticholinergic effects can be remembered using the saying "mad as a hatter, blind as a bat, hot as a hare, dry as a bone, red as a beet". _______________________________ 🔥 FREE NOTES - https://www.simplico.org/lectures/ant... 📚 Book & Flashcards - https://www.simplico.org _______________________________ Timestamps: 00:00 Anticholinergic Examples 00:40 Anticholinergic Mnemonic 01:05 Sympathetic vs Parasympathetic 03:16 Anticholinergic vs Sympathomimetic Toxicity 05:34 Anticholinergic Toxicity Symptoms 06:03 Anticholinergic Workup 08:00 Anticholinergic Management 09:29 Antidote Treatment _______________________________ Thanks for watching!