Oligonucleotide Analysis. Practical Implementation Approaches for HPLC and LC-MS Analyses

Oligonucleotides represent a diverse class of therapeutics that provide great promise to treat disease, but can pose a number of analytical challenges to scientists. In this webinar, we will present ion exchange and reversed-phase-ion-pair approaches to the separation of nucleic acids, separation examples of from small modified RNA, phosphothioated oligonucleotides, plasmid uncoiled and supercoiled DNA.