Andrew Pieper: Recent Evidence that Advanced Alzheimer’s Disease May be Reversible

In this episode I talk with Case Western Reserve University Professor Andrew Pieper about how it might be possible to restore neuroplasticity and cognition in Alzheimer’s disease. The conversation focuses on a recently published study from his laboratory which shows that a chemical called P7C3-A20 that restores energy balance in brain cells can reverse brain pathology and restore cognitive function in a mouse model of Alzheimer’s disease. LINKS Pieper laboratory: https://www.harringtondiscovery.org/a... Article discussed in this podcast: https://www.cell.com/action/showPdf?p...

Melissa Barker-Haliski: Neural Network Hyperexcitability, Epilepsy, Aging, and Alzheimer’s Disease
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Melissa Barker-Haliski: Neural Network Hyperexcitability, Epilepsy, Aging, and Alzheimer’s Disease

Maria Ioannou: Lipid Dynamics, Brain Cell Stress, ApoE, and Neurodegenerative Disorders
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Maria Ioannou: Lipid Dynamics, Brain Cell Stress, ApoE, and Neurodegenerative Disorders

Joseph Takahashi: Circadian Clock Proteins, Metabolism, Neuroplasticity, and Aging
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Joseph Takahashi: Circadian Clock Proteins, Metabolism, Neuroplasticity, and Aging

Dwight Bergles:  Oligodendrocyte Precursor Cells in Neuroplasticity, Aging, Injury, and Disease
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Dwight Bergles: Oligodendrocyte Precursor Cells in Neuroplasticity, Aging, Injury, and Disease

How to Treat Biliary Tract Cancer – Treatment Algorithm with Dr. Suneel Kamath
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How to Treat Biliary Tract Cancer – Treatment Algorithm with Dr. Suneel Kamath

Neurobiology of Aging Lecture #4: Aging and Neurodegenerative Disorders; AD, PD, ALS, and FTD.
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Neurobiology of Aging Lecture #4: Aging and Neurodegenerative Disorders; AD, PD, ALS, and FTD.

Hillel Adesnik - How Neural Ensembles Integrate Sensory Information and Encode Perception
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Hillel Adesnik - How Neural Ensembles Integrate Sensory Information and Encode Perception

Episode 52: Understanding Myocardial Bridges: Diagnosis, Surgery & Treatment with Dr. Khaled Ziada
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Episode 52: Understanding Myocardial Bridges: Diagnosis, Surgery & Treatment with Dr. Khaled Ziada

Dominik Fischer:  Gene Therapy for Vision Loss
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Dominik Fischer: Gene Therapy for Vision Loss

Ideas for Tomorrow | Larry Culp, Chairman and CEO, GE and CEO, GE Aerospace
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Ideas for Tomorrow | Larry Culp, Chairman and CEO, GE and CEO, GE Aerospace

Liqun Luo: Signaling Pathways and Molecular Codes for the Assembly of Neural Circuits
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Liqun Luo: Signaling Pathways and Molecular Codes for the Assembly of Neural Circuits

Unlocking Energy: Overcoming Hashimoto's, Chronic Fatigue | Dr. Evan Hirsch | Dr. Anshul Gupta
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Unlocking Energy: Overcoming Hashimoto's, Chronic Fatigue | Dr. Evan Hirsch | Dr. Anshul Gupta

Alex Kwan: Cutting-Edge Technologies Reveal How Psilocybin Rewires the Brain’s Neural Networks
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Alex Kwan: Cutting-Edge Technologies Reveal How Psilocybin Rewires the Brain’s Neural Networks

New treatments bring hope in the fight against Alzheimer’s
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New treatments bring hope in the fight against Alzheimer’s

Michael Tadross: Targeting Drugs to Specific Neurons to Understand Brain Functions and Treat Disease
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Michael Tadross: Targeting Drugs to Specific Neurons to Understand Brain Functions and Treat Disease

Bassem Hassan: Normal Functions of the Amyloid Precursor Protein in the Developing and Adult Brain
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Bassem Hassan: Normal Functions of the Amyloid Precursor Protein in the Developing and Adult Brain

David Bennett: Research on Rare Gene Mutations is Revolutionizing Pain Treatment for Everyone
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David Bennett: Research on Rare Gene Mutations is Revolutionizing Pain Treatment for Everyone

Nick Betley: A Few Neurons at the Bottom of the Brain Control Pain, Inflammation, and Endurance
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Nick Betley: A Few Neurons at the Bottom of the Brain Control Pain, Inflammation, and Endurance

Tomás Ryan: Competition Between Memory Engrams and The Importance of Forgetting
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Tomás Ryan: Competition Between Memory Engrams and The Importance of Forgetting

Raise Plow Podcast | Mesothelioma surgical treatment and more with Christopher Towe, MD
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Raise Plow Podcast | Mesothelioma surgical treatment and more with Christopher Towe, MD