Neurobiology of Aging Lecture #4: Aging and Neurodegenerative Disorders; AD, PD, ALS, and FTD.

In this lecture I describe how changes occurring in the brain during normal aging set contribute to the pathogenesis of Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, and frontotemporal dementia. Cellular and molecular hallmarks of aging predispose brain cells to neurodegenerative orders with environmental and genetic factors determining if and when the disease manifests. LINKS: Review articles: https://pmc.ncbi.nlm.nih.gov/articles... https://pmc.ncbi.nlm.nih.gov/articles... https://pmc.ncbi.nlm.nih.gov/articles...

Neurobiology of Aging Lecture #5 – Mechanisms by Which Lifestyle Choices Affect Brain Aging
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Neurobiology of Aging Lecture #5 – Mechanisms by Which Lifestyle Choices Affect Brain Aging

Joseph Takahashi: Circadian Clock Proteins, Metabolism, Neuroplasticity, and Aging
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Joseph Takahashi: Circadian Clock Proteins, Metabolism, Neuroplasticity, and Aging

Hillel Adesnik - How Neural Ensembles Integrate Sensory Information and Encode Perception
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Hillel Adesnik - How Neural Ensembles Integrate Sensory Information and Encode Perception

Maria Ioannou: Lipid Dynamics, Brain Cell Stress, ApoE, and Neurodegenerative Disorders
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Maria Ioannou: Lipid Dynamics, Brain Cell Stress, ApoE, and Neurodegenerative Disorders

Death Is Not The End — Feynman Explains What Physics Says About Dying
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Death Is Not The End — Feynman Explains What Physics Says About Dying

LIVE: Conan O’Brien speaks at Harvard graduation ceremony (full)
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LIVE: Conan O’Brien speaks at Harvard graduation ceremony (full)

Liqun Luo: Signaling Pathways and Molecular Codes for the Assembly of Neural Circuits
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Liqun Luo: Signaling Pathways and Molecular Codes for the Assembly of Neural Circuits

David Bennett: Research on Rare Gene Mutations is Revolutionizing Pain Treatment for Everyone
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David Bennett: Research on Rare Gene Mutations is Revolutionizing Pain Treatment for Everyone

Dwight Bergles:  Oligodendrocyte Precursor Cells in Neuroplasticity, Aging, Injury, and Disease
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Dwight Bergles: Oligodendrocyte Precursor Cells in Neuroplasticity, Aging, Injury, and Disease

Alex Kwan: Cutting-Edge Technologies Reveal How Psilocybin Rewires the Brain’s Neural Networks
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Alex Kwan: Cutting-Edge Technologies Reveal How Psilocybin Rewires the Brain’s Neural Networks

GoldLab Symposium 2026: Gary Stormo
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GoldLab Symposium 2026: Gary Stormo

HDA Conference - Abnormal Mental States & Behaviours in HD - Hugh Richards
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HDA Conference - Abnormal Mental States & Behaviours in HD - Hugh Richards

Melissa Barker-Haliski: Neural Network Hyperexcitability, Epilepsy, Aging, and Alzheimer’s Disease
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Melissa Barker-Haliski: Neural Network Hyperexcitability, Epilepsy, Aging, and Alzheimer’s Disease

Nick Betley: A Few Neurons at the Bottom of the Brain Control Pain, Inflammation, and Endurance
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Nick Betley: A Few Neurons at the Bottom of the Brain Control Pain, Inflammation, and Endurance

Bassem Hassan: Normal Functions of the Amyloid Precursor Protein in the Developing and Adult Brain
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Bassem Hassan: Normal Functions of the Amyloid Precursor Protein in the Developing and Adult Brain

IACS Webinar with Philipp E. Scherer, PhD
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IACS Webinar with Philipp E. Scherer, PhD

Sarah Paine - Why Putin and Xi can't escape geography
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Sarah Paine - Why Putin and Xi can't escape geography

Dominik Fischer:  Gene Therapy for Vision Loss
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Dominik Fischer: Gene Therapy for Vision Loss

Michael Tadross: Targeting Drugs to Specific Neurons to Understand Brain Functions and Treat Disease
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Michael Tadross: Targeting Drugs to Specific Neurons to Understand Brain Functions and Treat Disease

Intro to Neuroscience
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Intro to Neuroscience