Cyclic vs. Daily Progesterone: The Case for Rhythmic HRT | Felice Gersh, MD

In this talk, I explain why progesterone should be given cyclically—not nightly—when using menopause hormone therapy. I review the history of estrogen and progestin use, the problems with medroxyprogesterone acetate, and why major studies like KEEPS and ELITE used cyclic progesterone. I also share why optimal estradiol dosing matters, how growth factors restore tissues, and why our bodies need hormone rhythms to regulate receptors and support healthy longevity. If you want hormone therapy for optimization—not just hot flash relief—this video will help you understand why cycling progesterone is essential. Watch for my latest Instagram lives at   / dr.felicegersh   I am a full time practicing doctor. I see patients in my office in Irvine, CA and worldwide via telemedicine. If you need more healthcare assistance than I can provide in a video series, please contact my office: https://integrativemgi.com/​​ #CyclicProgesterone #estradiol #progesterone #MHT #HRT #HormoneTherapy #MenopauseRelief #HealthyAging #WomensHormones #IntegrativeMedicine #DrFeliceGersh #dosematters ---- Contents of this video -------------------------- 00:00 Why We’re Talking About Cyclic Progesterone 01:00 A Brief History of Estrogen and Progesterone Therapy 04:30 The Rise of Premarin and Provera 07:00 WHI, HERS, and the Problem with Daily Progestins 09:30 KEEPS, ELITE, and Cyclic Progesterone Use 11:30 Estradiol Dose Matters: Growth Factors and Tissue Repair 13:30 “If You Grow It, You Must Shed It” – Why Rhythm Matters 15:30 Receptor Regulation and the Role of Rhythmic Hormones 18:00 Why Monthly Bleeding Isn’t a Drawback 20:30 Final Thoughts: Mimicking Nature with Cyclic Progesterone