Neurotransmitter: Glutamate | Excitatory neurotransmitter | Neurology lecture series

Neurology playlist link: Glutamate is the main excitatory neurotransmitter of the central nervous system and is essential for normal brain function. In this neurology lecture, we explain what glutamate is, how it acts at the synapse, and why it is critically important in learning, memory, and neural communication. This video covers the basic mechanism of glutamatergic neurotransmission, including presynaptic release, postsynaptic receptor activation, and signal termination. You will learn about the major glutamate receptors—AMPA, NMDA, kainate (ionotropic) and metabotropic glutamate receptors (mGluRs)—and how they contribute to fast and slow excitatory signaling in the brain. Special emphasis is given to the NMDA receptor, its voltage-dependent Mg²⁺ block, Ca²⁺ permeability, and its role in synaptic plasticity and long-term potentiation (LTP), which form the cellular basis of learning and memory. The concept of excitatory postsynaptic potentials (EPSPs) is explained in a simple, exam-oriented manner. The lecture also discusses glutamate excitotoxicity, a key mechanism underlying neuronal injury in conditions such as stroke, traumatic brain injury, epilepsy, Alzheimer’s disease, and ALS. Clinical correlations are included to help students connect basic neuroscience with neurological disorders. This video is ideal for medical students, neurology residents, and neuroscience learners, and is especially useful for USMLE, NEET-PG, INI-CET, and other medical entrance exams. Clear explanations, simple diagrams, and high-yield points make this lecture a strong foundation for understanding excitatory neurotransmission in the brain. For Notes, flashcards, daily quizzes, and practice questions follow Instagram page:   / animatedbiologywitharpan   Facebook page: https://www.facebook.com/Animated-bio... Follow me on other social media - Facebook :   / arpan.parich.  . Instagram :   / arpanparichha   Linked in :   / arpan-pari.  . Twitter : https://twitter.com/arpan_parichha?la... Link to my other channel - Lets crack bio exams    / @medsimplifiedin5min   The Nerd Medic YouTube channel: Youtube:    / thenerdmedic00   Instagram:   / ayan_parichha00.  . Facebook:   / poetsoflens   For Physics part of bio exams - Physics for IIT JAM biotechnology    / @physicsforiitjambiotechnol9456   #animated_biology #animated_biology_with_arpan #biology #bio_facts #CSIR_NET #IIT_JAM #IIT_JAM_BT #biotechnology #bioscience #biological_sciences #microbiology #genetics #zoology #molecular_biology #cell_biology #botany #immunology #ecology