Physostigmine for Anticholinergic Toxicity? | Toxicology | #CodeBlueDebrief

👾 Physostigmine is a reversal agent for anticholinergic toxicities. By inhibiting acetylcholinesterase, increased acetylcholine becomes available at the synapses. It is an excellent drug to reverse antimuscurinic poisonings. Unfortuanetely, it has a negative stigma from prior case reports associated with TCA deaths. Website: www.pharmwyze.com Shop: www.pharmwyze.com/shop Donate $5: www.pharmwyze.com//_paylink/AY78_L7r Social Links: links.pharmwyze.com DrugQueryInbox Request: https://pharmwyze.hopp.to/drugqueryinbox Streaming Platforms: https://pharmwyze.hopp.to/podstreams Patreon: www.patreon.com/pharmwyze Paypal Donation: https://pharmwyze.hopp.to/paypaldonate PHARMWYZE SITREP Newsletter: https://www.pharmwyze.com/sitrepnewsl... References Newton RW. JAMA . 1975 Mar 3;231(9):941-3. Pentel P, Peterson CD. Ann Emerg Med . 1980 Nov;9(11):588-90. Wang GS et al. Clin Toxicol (Phila). 2021 Aug;59(8):698-704. Watkins JW et al. J Med Toxicol. 2015 Jun;11(2):179-84. Fratta KA, Ginder M, Haggerty DA. The Journal of Emergency Medicine, Vol. 65, No. 4, pp. e366–e368, 2023 McCoy CE, Honda R. J Educ Teach Emerg Med. 2023 Jan 31;8(1):S25-S47. Elkhazeen A et al. J Forensic Sci . 2023 Jan;68(1):339-342. Nishtala PS, Salahudeen SJ, Hilmer SN. Expert Opin Drug Saf . 2016 Jun;15(6):753-68. https://www.fda.gov/drugs/drug-shorta... https://www.ashp.org/drug-shortages/c... #pharmacist #pharmwyze #pharmfax #criticalcare #emergencymedicine #studentpharmacist #nursingstudent #medicalstudent #pharmacy #medicine #nursing #meded #shorts #rxshorts #medigram #thelab #medshed #foamed #emrx #pharmacology #pharmacokinetics #cardiology #neurology #infectiousdisease #mechanism #mechanismofaction #moa #drugs #ketamine #propofol #etomidate #fentanyl #calcium #mtp #massivetransfusion #ems #emergency #antibiotics #metabolism