Ozempic Face? Zepbound Butt? The Questions Everyone’s Asking!

This week, Laraine and Christopher are home from Obesity Week 2025 in Atlanta — tired, grateful, and full of stories. They’ve lost more than 150 pounds combined using GLP-1 medications and are sharing what they learned at the world’s biggest obesity conference — from doctors’ reactions to their booth, to the latest research, to what the new White House GLP-1 pricing plan could mean for all of us. They’re also answering 18 viewer questions, including: plateaus, side effects, muscle loss, compounded vs. branded tirzepatide, whether the new KwikPen replaces vials, and how long you’ll need to stay on these medications. If you’ve ever wondered about switching from Zepbound to compounded tirzepatide, how to talk to your doctor, or what to expect at maintenance, this episode is for you. Topics Covered: • Our weekly weigh-in: Laraine’s 50-lb loss, Christopher’s 100-lb milestone • Behind the scenes at Obesity Week 2025: what doctors really said • The White House GLP-1 pricing plan explained, what’s real, what’s missing, and what we still don’t know • How BMI, Medicare coverage, and the new multi-dose KwikPen might change access • Why some doctors still don’t understand YouTube or patient advocacy • How to start GLP-1s with your family doctor or telehealth • Side effects, constipation tips, and the fiber gummies Laraine actually uses • Muscle loss and “Ozempic face” what’s real and what’s overblown • Why we don’t plan to stop taking GLP-1s, ever • Viewer Q&A: from surgery meal prep to fatigue and brain fog To receive 20% off your Purchase of Biocare Protein Bars or Shakes, visit https://biocarenutrition.com/DOWNSIZED and enter the discount code DOWNSIZED To Purchase LARAINE’S BIOCARE FAVORITES https://biocarenutrition.com/products... and enter the discount code DOWNSIZED to receive an additional 20% Start your weight loss journey today! We use Mochi Health: https://joinmochi.com/. Use Laraine’s code for $40 off: QIYGO8. Me Again Iphone GLP-1 App: https://apps.apple.com/us/app/meagain... Get your Hume BodyPod today and use our exclusive Downsized code for an extra 20% off on top of the sitewide sale—up to 50% total savings! 👉 Use our Code: THEDOWNSIZED Link to purchase: https://humehealth.com//discount/THED... LINKS AMAZON GLP-1 Companion Product Store: https://www.amazon.com/shop/downsized As an Amazon Associate, I earn from qualifying purchases. Downsized Website: Https://Thedownsized.Org/ Book The Downsized At Sea Cruise 2026: Https://Thedownsized.Org/Downsized-At... FOR SPONSORSHIPS, BRAND DEALS & COLLABS: https://thedownsized.org/contact/ This video is for educational purposes only and is not medical advice. GLP-1 medications such as semaglutide (Wegovy, Ozempic) and tirzepatide (Mounjaro, Zepbound) can cause serious side effects, including thyroid tumor risk, pancreatitis, gallbladder problems, and kidney issues, as well as common effects like nausea, vomiting, and diarrhea. We have no financial or advertising relationship with Eli Lilly or Novo Nordisk. Always talk to your healthcare provider for full safety information. 00:00 Welcome to The Downsized 00:16 Weekly Weigh-In 05:55 Obesity Week Conference Highlights 11:21 Challenges and Learnings from the Conference 23:05 Viewer Questions and Answers 23:25 Did Laraine hit a plateau? 25:39 White House GLP-1 price plan — what’s really in it? 26:05 What’s changing with LillyDirect pricing? 26:47 Does this help people without comorbidities? 30:00 How long do we stay on GLP-1s? 31:56 Can your family doctor prescribe GLP-1s? 33:04 Frustrations with Traditional Healthcare 34:19 Side Effects of Medication 35:48 Concerns About Muscle Loss 40:47 What sugar-free gummies does Laraine use? 41:58 Would you ever stop GLP-1s to test it? 44:26 Do women in their 60s lose weight slower? 45:36 Is the pen stronger than the vial? 47:02 Do GLP-1s cause brain fog? 48:53 Ozempic Face? Zepbound Butt? Will GLP-1s shrink my face or butt? 51:08 Do you buy both Zepbound and compounded? 52:02 When’s the best time to take your shot? 52:58 Why do vial expiration dates differ? 54:54 What meals work after surgery? 56:39 No weight loss yet — what should I do? 59:28 Upcoming Events and Community Engagement

Why Are People So Judgmental About GLP-1s?
▶︎

Why Are People So Judgmental About GLP-1s?

A GLP-1 Dietitian Finally Said This Out Loud!
▶︎

A GLP-1 Dietitian Finally Said This Out Loud!

Shot or Pill: The GLP-1 Question That Will Define 2026
▶︎

Shot or Pill: The GLP-1 Question That Will Define 2026

Not Obese Anymore! Can You Still Get GLP-1s?
▶︎

Not Obese Anymore! Can You Still Get GLP-1s?

Everything I WISH I KNEW about Zepbound! How I lost 65 pounds.
▶︎

Everything I WISH I KNEW about Zepbound! How I lost 65 pounds.

Is Obesity REALLY a Disease… or Just ‘Put the Fork Down’?” WEEKLY WEIGH-IN
▶︎

Is Obesity REALLY a Disease… or Just ‘Put the Fork Down’?” WEEKLY WEIGH-IN

She Started the GLP-1 Microdosing Trend — Here's What She's Saying Now | Dr. Tyna Moore
▶︎

She Started the GLP-1 Microdosing Trend — Here's What She's Saying Now | Dr. Tyna Moore

Ashley Koff: The GLP-1 Conversation Most People Are Missing
▶︎

Ashley Koff: The GLP-1 Conversation Most People Are Missing

Am I On Ozempic? The Truth About My 48 lb Weight Loss at 50+ (Honest Reality)
▶︎

Am I On Ozempic? The Truth About My 48 lb Weight Loss at 50+ (Honest Reality)

New Study Shows How To Keep Weight Off When No Longer Using GLP1's (Doctor Reation) | Solo Ep 247
▶︎

New Study Shows How To Keep Weight Off When No Longer Using GLP1's (Doctor Reation) | Solo Ep 247

Avoid Mistakes! WHEN to Increase Tirzepatide (And When NOT To!) // BIOptimizers
▶︎

Avoid Mistakes! WHEN to Increase Tirzepatide (And When NOT To!) // BIOptimizers

20 Questions About GLP-1s You’ve Been Too Afraid to Ask: Zepbound, Wegovy, Ozempic, Mounjaro
▶︎

20 Questions About GLP-1s You’ve Been Too Afraid to Ask: Zepbound, Wegovy, Ozempic, Mounjaro

Your Burning GLP-1 Questions Answered: Loose Skin, Hair Loss & More
▶︎

Your Burning GLP-1 Questions Answered: Loose Skin, Hair Loss & More

Oprah and Yale Researcher Break Down How Weight Loss Drugs Affect the Brain
▶︎

Oprah and Yale Researcher Break Down How Weight Loss Drugs Affect the Brain

12 Things You Should NEVER Mix with Ozempic or Mounjaro
▶︎

12 Things You Should NEVER Mix with Ozempic or Mounjaro

Hard truths about why you're not losing weight on a GLP-1
▶︎

Hard truths about why you're not losing weight on a GLP-1

60lbs Down with Tirzepatide: A Nurse’s Honest Review
▶︎

60lbs Down with Tirzepatide: A Nurse’s Honest Review

Oprah and Obesity Doctors on the New Way to Lose Weight | The Life You Want Class | Oprah Daily
▶︎

Oprah and Obesity Doctors on the New Way to Lose Weight | The Life You Want Class | Oprah Daily

Serena Williams and Oprah on Deciding to Take GLP-1 Medications
▶︎

Serena Williams and Oprah on Deciding to Take GLP-1 Medications

The Big GLP-1 Debate: What the Science ACTUALLY Says
▶︎

The Big GLP-1 Debate: What the Science ACTUALLY Says