[TALK 10] Biophysics in Drug Discovery - Dillon Rinauro

Biophysics in Drug Discovery Speakers: Dillon Rinauro, AstraZeneca, UK In this video, Dillon gives an overview of drug discovery process at AstraZeneca and how biophysics contributes at the different stages. He describes the range of biophysical tools used at AstraZeneca. He details examples of how these tools have answered critical questions such as reagent quality control, hit identification and validation. He shows how different techniques can overcome an apparent potency limit highlighting their strengths and weaknesses. He lastly looks at using biophysical techniques to understand molecular glues. Read more about AstraZeneca’s work here: https://www.astrazeneca.com/r-d.html You can find more videos from the LMB 2025/26 Solving Problems with Molecular Techniques series here:    • Molecular Techniques Training Seminars 202...   -- About the MRC Laboratory of Molecular Biology (LMB): The LMB is one of the world's leading research institutes. Discoveries and inventions developed at the LMB, for example DNA sequencing and methods to determine the structure of proteins, have revolutionised all areas of biology. Our scientists work to advance understanding of biological processes at the molecular level. This information will help us to understand the workings of complex systems, such as the immune system and the brain, and solve key problems in human health. More links: Official Site: https://mrclmb.ac.uk/ Facebook:   / mrc.lmb   Bluesky: https://bsky.app/profile/mrclmb.bsky.... Instagram:   / mrc_lmb   LinkedIn:   / mrc-laboratory-of-molecular-biology   Click here to subscribe to MRC Laboratory of Molecular Biology on YouTube: https://www.youtube.com/user/LMBCambr...