The Estrobolome: How Your Patient's Gut Is Recycling Estrogen EP: 101

Her estrogen reads optimal and she is still symptomatic. The reason is the estrobolome, and the gut is recycling estrogen. Nico Misleh, MSN, FNP-C breaks down how the gut decides whether estrogen leaves the body or returns to circulation, why this drives estrogen dominance, PCOS, PMDD, fibroids, and breast cancer risk, and the targeted interventions that help patients clear estrogen instead of recirculating it. Chapters 00:00 Why the estrobolome matters 01:43 What the estrobolome actually is 02:34 The patient who looks optimal on labs 05:43 External products vs internal gut exposure 08:12 Beta-glucuronidase and how estrogen gets freed 12:05 Enterohepatic recirculation and accumulation 15:24 Industrialized guts and higher recycling capacity 18:39 The estrobolome and breast cancer risk 22:39 Menopause: why estrogen can stay high 26:13 PCOS, endometriosis, PMDD, and endotoxin 32:10 Practical interventions: the raw carrot 35:57 Coffee, gut motility, and phase two detox 38:11 Glycine, taurine, progesterone, and thyroid 40:27 The framing to land with patients Learn more about the Master Course: https://bit.ly/4rOX4Xu HRTU Newsletter: https://nicomislenp.kit.com/8050eeea5f Join the HRT University Facebook Group:   / 1179376819949373   #HRT #Estrobolome #HormoneHealth