Lecture On Renal Cell Carcinoma vs. Wilms Tumor: Pathology, Diagnosis & Staging | MBBS

In this practical pathology session, we conduct a deep dive into the gross and microscopic features of Renal Cell Carcinoma (RCC) and Wilms Tumor (Nephroblastoma). Designed for medical students and pathology trainees, this lecture covers differential diagnosis, pathological staging (TNM), and key identifying features for practical examinations. Video Chapters: 00:00:00 - Introduction & Differential Features: RCC vs. Wilms Tumor 00:01:34 - Renal Cell Carcinoma (RCC): Epidemiology, Gross Features & Appearance 00:05:45 - Microscopic Pathology of RCC (Clear Cell, Papillary Patterns) 00:09:14 - Wilms Tumor (Nephroblastoma): Epidemiology & Pathological Features 00:11:05 - Microscopic Components of Wilms Tumor (Blastemal, Epithelial, Stromal) 00:12:43 - Predisposing Genetic Factors (VHL Gene, WT1 Gene) 00:14:08 - Clinical Symptoms & Diagnostic Investigations 00:15:41 - TNM Staging System for Renal Tumors 00:19:53 - Practical Exam Guide: Specimen Identification & Variegated Appearance Key Learning Objectives: Distinguishing RCC (common in adults) from Wilms tumor (common in children). Identifying "variegated appearance" in gross pathology (necrosis, hemorrhage, cystic change). Understanding the TNM staging system for renal tumors. Key microscopic markers and genetic predispositions (VHL, WT1). #Pathology #MBBS #RenalCellCarcinoma #WilmsTumor #Nephroblastoma #MedicalEducation #KidneyTumors #ClinicalPathology #SantiniketanMedicalCollege SANTINIKETAN MEDICAL COLLEGE & HOSPITAL Real Classroom Demonstration/Lecture On: PATHOLOGY by Dr. Madhurima Chakraborty (MBBS Batch: (2024-25) Conducted on: 08-07-2026