Lecture On Gestational Trophoblastic Disease: Hydatidiform Mole & Choriocarcinoma | Pathology | MBBS

Master the Pathology of Gestational Trophoblastic Diseases! 🩺🔬 In this comprehensive pathology lecture from Santiniketan Medical College & Hospital (2024-2025 Batch), we take a deep dive into the embryology, histology, and pathology of Gestational Trophoblastic Diseases (GTD). This class is highly beneficial for MBBS students, pathology residents, and medical board aspirants (NEET-PG, INICET, FMGE). We break down the clinical and microscopic features of molar pregnancies and malignant trophoblastic proliferations, ensuring you understand the core concepts required for exams and clinical practice. 📌 What you will learn in this lecture: • Basics of embryology, blastocyst formation, and placental anatomy. • Histology of Chorionic Villi and types of trophoblasts (Cytotrophoblast vs. Syncytiotrophoblast). • Hydatidiform Mole: Detailed morphological differences between Complete and Partial Moles. • The role of p57 Immunohistochemistry (IHC) in diagnosing molar pregnancies. • Clinical presentation, diagnosis, and the critical importance of serial Beta-hCG monitoring. • Choriocarcinoma: Gross appearance, aggressive hematogenous metastasis, and chemotherapy prognosis. ⏱️ Video Chapters (Click to skip to a topic): [00:00] Intro to Gestational Trophoblastic Diseases [02:14] Embryology, Blastocyst & Trophoblast Formation [05:09] Normal Placental Anatomy & Histology [08:08] Chorionic Villi Structure & Trophoblast Types [14:34] Overview of Placental Pathology [17:31] Hydatidiform Mole: Definition & Pathogenesis [19:19] Complete Mole: Morphology & p57 IHC Significance [26:25] Partial Mole: Fetal RBCs & Villi Scalloping [33:07] Clinical Diagnosis & Beta-hCG Monitoring [40:37] Choriocarcinoma: Pathology, Metastasis & Prognosis #MBBS #Pathology #GestationalTrophoblasticDisease #HydatidiformMole #Choriocarcinoma #MedicalStudent #NEETPG #PlacentaPathology #SantiniketanMedicalCollege #Histopathology #Gynecology #MedicalCollege SANTINIKETAN MEDICAL COLLEGE & HOSPITAL Real Classroom Demonstration/Lecture On: PATHOLOGY by Dr. Sankha Subhra Sinha (MBBS Batch: (2024-25) Conducted on: 10-07-2026