How Life Works: the new biology of meaning with Philip Ball (science writer, chemist & physicist)

#meaning #newbiology #philosophy #genes #philipball #howlifeworks #beyondgenes #waymaking https://philipball.co.uk/latest-books/ https://open.substack.com/pub/lovephi... Andrea Hiott in conversation with British science writer Philip Ball (former Nature editor; trained chemist and physicist) to discuss his book How Life Works and why the popular idea “it’s all in the genes” is untenable. Ball argues biology is shifting beyond mechanistic, bottom-up “blueprint” metaphors toward a view of organisms as open, adaptive informational systems with complex genotype–phenotype relations, constant interaction across levels (genes to ecosystems), and robust behavior emerging from “committee-like” molecular collectives. They discuss why biology has avoided purpose, teleology, and meaning, yet living systems make contextual value judgements and goal-directed decisions, with continuity from cells to human minds and emotions, emphasizing embodiment and symbiosis. Ball links these themes to his prostate cancer diagnosis while finishing the book, reflecting on mortality, persistence of patterns and information through art and writing, and the open-endedness of life and evolution, ending with love as a real evolved capacity. Philip's website: https://philipball.co.uk/latest-books/ 00:00 Welcome and Guest Intro 00:35 Why Biology Is Shifting 02:09 Cancer, Meaning, and Patterns 04:37 Challenging Gene Determinism 11:03 Beyond the Machine Metaphor 17:52 Purpose and Teleology in Life 23:58 Messiness and Higher-Level Causation 31:54 Meaning Making in Cells 38:10 Embodiment and the Mind-Body Link 41:20 Embodied Minds 42:23 Nested Bodies and Meaning 43:52 Molecular Caring and Committees 45:02 Physics of Collectivity 47:19 Universality From Traffic to Cells 51:11 Leaky Layers in Living Systems 53:20 Beyond E. coli to Elephants 55:49 Caring as a New Metaphor 57:44 Symbiosis Parasites and Affordances 01:03:23 Brains Agency and Emotions 01:08:10 Mortality and Whirlpools of Meaning 01:15:42 Uniqueness Open-Ended Evolution 01:18:25 Love as Evolutionary Reality

#88 How Life Works Beyond Genes: the New Biology of Meaning with scientist and author Philip Ball
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