Vitamin C for Sepsis and Severe ARDS

In a 2019 randomized trial, high-dose vitamin C infusion did not reduce organ failure scores at 96 hours or improve biomarkers of inflammation and vascular injury at 168 hours in patients with sepsis-induced severe acute respiratory failure in U.S. intensive care units (ICUs). Alpha A. Fowler III, MD of Virginia Commonwealth University in Richmond presents findings from the CITRIS-ALI trial at the European Society of Intensive Care Medicine (ESICM) 32nd Annual Congress, LIVES 2019, on October 2 in Berlin. See https://ja.ma/2qJP94f for complete trial details. Video used with permission.