Medical Genetic EP.2 | Mendelian and Non-Mendelian Disorders

Welcome back to the Medical Genetics series! In this episode, we dive deep into the world of genetic inheritance, covering both Mendelian and Non-Mendelian patterns. Understanding these patterns is crucial for predicting the risk of genetic disorders and providing accurate genetic counseling. In this video, we cover: Basic Terminology: Locus, Allele, Genotype, and Phenotype. Mendelian Inheritance: Autosomal Dominant (AD): Traits, pedigree patterns, and examples like Neurofibromatosis Type 1 and Marfan Syndrome. Autosomal Recessive (AR): Horizontal transmission, carrier risks, and examples like Thalassemia and Wilson Disease. X-Linked Dominant & Recessive: Gender-specific patterns and clinical cases such as Hemophilia and G6PD deficiency. Non-Mendelian Inheritance: Mitochondrial Inheritance: Maternal transmission and Heteroplasmy. Complex Concepts: Incomplete penetrance, Variable expressivity, and Anticipation. Genomic Imprinting: Prader-Willi and Angelman syndromes. Mosaicism and Uniparental Disomy. Risk Assessment: How to use Punnett squares and the 2/3 Rule to calculate genetic risks in clinical scenarios. Whether you are a medical student, a healthcare professional, or just curious about genetics, this guide will help simplify these complex topics with clear examples and pedigree analysis. 📌 NinjaBoss: Medical Genetic Playlist    • NinjaBoss: Medical Genetic   Timestamps: 0:00 Intro & Basic Terms 1:47 Pedigree Symbols 4:19 Autosomal Dominant (AD) 6:55 Autosomal Recessive (AR) 11:00 X-Linked Dominant 12:12 X-Linked Recessive 15:19 Non-Mendelian Inheritance 16:46 Mitochondrial Inheritance 17:34 Special Genetic Phenomena 23:22 Risk Calculation & Case Study 27:18 Outro If you found this video helpful, don't forget to Like, Subscribe, and hit the Notification Bell to stay updated with the NinjaBoss Medical series! 👇    / @ninjaboss_th   #MedicalGenetics #MendelianInheritance #GeneticDisorders #USMLE #MedicalEducation #NinjaBoss