The Impact of Genetic Influences of MAOA, MAOB & COMT on Antidepressant Response

Antidepressants play a crucial role in managing depressive disorders, but their efficacy varies widely among individuals. Genetic factors have been identified as significant contributors to interindividual variability in antidepressant response. In this opportunity, we will discuss the impact of three key genes, Monoamine Oxidase A (MAOA), Monoamine Oxidase B (MAOB), and Catechol-O-Methyltransferase (COMT), on the response to antidepressant treatment. By examining the genetic variations within these genes and their potential implications for neurotransmitter metabolism and synaptic plasticity, we can gain valuable insights into personalized medicine approaches for depression treatment.