13 GLP-1 Tips Every Beginner Should Know

If you're new to GLP-1 medications or thinking about starting, this video is for you. In this beginner's guide, Laraine Durham shares the 13 things every new GLP-1 user should know before taking their first dose. After losing more than 50 pounds with tirzepatide and maintaining her weight loss for more than two years, she walks through the lessons she wishes someone had told her when she started. Whether you're taking Zepbound, Wegovy, oral Wegovy, Ozempic, Mounjaro, Found, compounded semaglutide, compounded tirzepatide, or preparing for next-generation medications like orforglipron, this video will help you start with confidence. You'll learn what to expect during your first weeks, how to choose a shot day, what to eat, how to manage common side effects, when to increase your dose, realistic weight loss expectations, and why tracking your progress and celebrating non-scale victories can make all the difference. In this video you'll learn: • How GLP-1 medications work • How to get your medication and supplies • Choosing your injection day and injection site • What to expect after your first dose • What to eat and how much protein you need • Managing nausea, constipation, fatigue, and other common side effects • Realistic weight loss expectations • Exercise and preserving muscle • Understanding titration and dose increases • Tracking progress beyond the scale • Why non-scale victories matter • Building a long-term support system The Downsized is hosted by Christopher and Laraine Durham, who together have lost more than 150 pounds using GLP-1 medications. They share their real-world experiences, explain the latest obesity research in plain English, interview leading obesity experts, and provide practical support for people living with the disease of obesity. +++++++++++++++++++++++++++++++++++++++ Start your weight loss journey today! We use Mochi Health: https://app.joinmochi.com/eligibility... Use Laraine’s code for $40 off: QIYGO8. Get your Hume BodyPod today and use our exclusive Downsized code for up to 20% total savings! 👉 Use our Code: THEDOWNSIZED Link to purchase: https://humehealth.com//discount/THED... SHOP OUR AMAZON STORE: https://a.co/d/0gGe1MYq BOOK THE DOWNSIZED AT SEA CRUISE 2026: https://thedownsized.org/downsized-at... DOWNSIZED WEBSITE: https://thedownsized.org/ JOIN CLUB DOWNSIZED: https://www.youtube.com/@thedownsized... FOR SPONSORSHIPS, BRAND DEALS & COLLABS: https://thedownsized.org/contact/ +++++++++++++++++++++++++++++++++++++++ 00:00 Starting Your GLP-1 00:48 Meet Laraine 01:57 How GLP-1s Work 02:31 1. GET YOUR MEDICATION 03:42 2. Gather Your Supplies 04:23 3. PICK YOUR SHOT DAY 05:59 4. WHAT IF I DON’T FEEL ANYTHING? 06:23 5. WHAT IF I’M HUNGRY? WHAT SHOULD I EAT? 07:53 6. PREPARE FOR SIDE EFFECTS 09:04 7. SET REALISTIC EXPECTATIONS – THIS IS NOT FAST WEIGHT LOSS. 10:43 8. TRACK YOUR PROGRESS 11:13 9. DO I HAVE TO EXERCISE? 11:54 10. TITRATION AND WHAT DOES THAT MEAN? 12:58 11. TAKE SOME PICTURES OF YOURSELF. 13:46 12. CELEBRATE NSV’S 14:45 13. BUILD A SUPPORT SYSTEM 15:20 Resources