Virology Lectures 2025 #2: The Infectious Cycle

Everything that happens when a virus enters a cell is called the infectious cycle. In this lecture we discuss the different parts of the infectious cycle and how they can be studied. These include assay of infectious virus particles by plaque assay, multiplicity of infection, and the particle to pfu ratio. Physical methods for detecting viruses include hemagglutination, serological techniques, polymerase chain reaction, and high-throughput sequencing. We show how these methods were used to identify in early 2020 the new pandemic coronavirus SARS-CoV-2. Become a patron of Virology Lectures at https://microbe.tv/contribute ——————————— OUR SCIENCE PODCASTS ——————————— •This Week in Virology https://bit.ly/30uUhrX This Week in Parasitism https://bit.ly/3ndUNUZ •This Week in Microbiology https://bit.ly/33tOUeO •Urban Agriculture http://microbe.tv/urbanag •This Week in Evolution https://bit.ly/3ne1bf5 •Immune https://bit.ly/2HOyCVb •This Week in Neuroscience https://bit.ly/2So12Yd •Infectious Disease Puscast https://bit.ly/3K4EKF0 – Who Am I? – I’m Vincent Racaniello, Earth’s Virology Professor, and I believe that education should be free. I’m also a professor of virology at Columbia University in New York. I’ve been doing research on viruses since 1976, and teaching virology in classrooms and online since 1999. On this YouTube channel I share videos of my lectures, podcasts, and more. New videos are uploaded several times each week. I do not run ads on our work as it is disruptive to learning. We depend on your support. If you would like to support our work, go to https://www.microbe.tv/contribute/ MicrobeTV appreciates your donation and your support of our mission. Our budget and ongoing financial health rely on accounting for and accepting irrevocable, non-refundable donations from the public. Therefore, MicrobeTV considers all donations to be nonrefundable. Content in this video should not be construed as medical advice. ——————————————————————— #microbe #viruses #coronavirus #pandemic ———————————————————————