HVAC Performance Qualification (PQ) | Pharma HVAC Qualification Course – Section 8

Welcome to Section 8 of the HVAC Qualification Course by Pharmatalks. In this section, we explain the key requirements of HVAC Performance Qualification (PQ) in pharmaceutical and cleanroom facilities. Performance Qualification confirms that the HVAC system consistently maintains the required environmental conditions during normal operating conditions. It demonstrates that airflow, temperature, humidity, pressure differentials, air changes, and particle-control performance remain within approved acceptance criteria. Topics covered in this section: • What is HVAC Performance Qualification (PQ)? • Difference between OQ and PQ • HVAC testing under normal operating conditions • Airflow and air change rate verification • Temperature and humidity monitoring • Differential pressure and pressure cascade performance • Particle count and cleanroom environmental conditions • Recovery testing after door opening or disturbances • Seasonal performance considerations • PQ acceptance criteria, reports, deviations, and CAPA This section helps you understand how to confirm that an HVAC system performs reliably over time and continues to support GMP compliance, product quality, and patient safety. Subscribe to Pharmatalks for practical training on pharmaceutical HVAC, GMP, cleanrooms, qualification, validation, and quality assurance.