Xiidra® (lifitegrast ophthalmic solution) and Dry Eye Compliance: Supporting Adherence in Practice

Are you struggling with patient compliance with dry eye treatment? Discover how to enhance success with Xiidra and foster long-term relief for patients.† In this episode of Defocus Media, Dr. Darryl Glover, Dr. Jennifer Lyerly, and Dr. Mark Schaefer dive deep into strategies to improve compliance for dry eye patients using Xiidra. Learn how effective communication in the exam lane can empower patients to stay consistent with treatment, helping them achieve lasting relief. Join us as we discuss practical tips, from setting expectations to following up with patients and utilizing tools like specialty pharmacies to streamline prescriptions. Key takeaways include: • Recognizing signs and symptoms of dry eye disease. • Best practices for patient education to encourage compliance. • Tips on overcoming objections and setting realistic expectations. • Leveraging resources like BlinkRx and specialty pharmacies for hassle-free access. Like, subscribe, and hit the notification bell to stay updated on all things eye care! Follow us across platforms for more insights. Indication Xiidra® (lifitegrast ophthalmic solution) 5% is indicated for the treatment of signs and symptoms of dry eye disease (DED). Important Safety Information • Xiidra is contraindicated in patients with known hypersensitivity to lifitegrast or to any of the other ingredients. • In clinical trials, the most common adverse reactions reported in 5-25% of patients were instillation site irritation, dysgeusia and reduced visual acuity. Other adverse reactions reported in 1% to 5% of the patients were blurred vision, conjunctival hyperemia, eye irritation, headache, increased lacrimation, eye discharge, eye discomfort, eye pruritus and sinusitis. • To avoid the potential for eye injury or contamination of the solution, patients should not touch the tip of the single-use container to their eye or to any surface. • Contact lenses should be removed prior to the administration of Xiidra and may be reinserted 15 minutes following administration. • Safety and efficacy in pediatric patients below the age of 17 years have not been established. Please see full Prescribing Information for Xiidra at XIIDRA-ECP.COM. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800- FDA-1088. *The exact mechanism of action of Xiidra in dry eye disease is not known. †Xiidra significantly reduced symptoms of eye dryness at 2 weeks (based on Eye Dryness Score compared to vehicle) in 2 of 4 studies, with improvements observed at 6 and 12 weeks in all 4 studies. References: 1. Xiidra. Prescribing information. Bausch + Lomb Inc. 2. Amescua G, Ahmad S, Cheung AY, et al. Dry Eye Syndrome Preferred Practice Pattern®. Ophthalmology. 2024;131(4):P1-P49. doi:10.1016/j.ophtha.2023.12.041 ©2026 Bausch & Lomb Inc. XDR.0032.USA.26 -------------------------- Let’s Connect! Defocus Media on Social Media: 👁️ Instagram:   / defocusmedia   👁️ Facebook:   / defocusmedia   👁️ LinkedIn:   / defocus-media   👁️ Twitter:   / defocusmedia   👀 Website: https://defocusmediagroup.com/ 👀 Want to stay up to date on the latest trends and hottest topics in eye care? 📧 Sign up for our newsletter! https://share.hsforms.com/1rhZdAHr_Ss... -------------------------- DISCLAIMER: All content in this video and description, including infor­ma­tion, opinions, con­tent, ref­er­ences, and links, is for infor­ma­tional pur­poses only. The Author does not pro­vide any med­ical advice on the site. Noth­ing con­tained in this video or its description is intended to estab­lish a physician-patient rela­tion­ship, to replace the ser­vices of a trained physi­cian or health care pro­fes­sional, or oth­er­wise to be a sub­sti­tute for pro­fes­sional med­ical advice, diag­no­sis, or treatment. You should con­sult a licensed physi­cian or appropriately credentialed health care worker in your com­mu­nity in all mat­ters relat­ing to your health. Also, some of the links in this post may be affiliate links, meaning, at no cost to you, I will earn a small commission if you click through and make a purchase. All non-licensed clips are used for fair use commentary, criticism, and educational purposes.