Inside Patient #1’s Islet Transplant Without Immunosuppression

Join our newsletter: https://diabetech.info Follow me here:   / diabe_tech     / diabe_tech     / diabetechjustin   Learn about Omnipod 5*: https://bit.ly/Omnipod5Diabetech Learn about Eversense 365 CGM: https://diabetech.link/eversenseCGM I spoke with the first patient in a groundbreaking type 1 diabetes cure research trial using encapsulated neonatal pig islet cells—without immunosuppression. Six months after his transplant through the OPF-310 study led by Otsuka Pharmaceutical and University of Illinois Chicago, Michael Revland's insulin needs have been cut in half as the cells have begun maturing and producing insulin. We dive into how this porcine islet cell transplant works, why it differs from stem cell and donor islet trials, and the risks and rewards of pursuing insulin independence. He also shares why he declined an immunosuppression-based transplant study and the emotional highs and lows of being patient number one. Products I recommend: SugarDash: https://diabetech.link/sugardash Glowcose CGM Light: https://bit.ly/glowcoselight Diabetes Supplies: https://amzn.to/3N2Qs5F Production Gear I Use: https://amzn.to/4fWzVvS?r=lp&m=MnbegA... DISCLAIMERS: This podcast is not medical advice and is for educational purposes only Always consult with your medical team before making changes to your health care. *Omnipod (today's sponsor): 10-day trial eligibility may vary. Full terms and conditions apply. Visit omnipod.com/diabetech for clinical disclaimers, terms and important safety information. The Pod has an IP28 rating for up to 25 feet for 60 minutes. The Omnipod 5 Controller is not waterproof. Chapters: 02:35 Islet Cell Therapy 07:49 Military Diagnosis 22:09 The Search For Trials 32:47 Eledon Trial 41:15 OPF-310 Study 58:05 Post Implant Results 01:07:29 The Dark Period 01:10:11 It’s Working 01:23:09 What’s Next -- Product Link Disclosure -- In order to make a living and continue to create free content, I use affiliate links. This means if you make purchases through certain links, I may earn a small commission (at no extra cost to you).