Na perimenopausa : estradiol pode ou não pode ser usado???

Menopausal transition is one of the most misunderstood periods in female endocrinology—and perhaps the biggest mistake is treating it as a simple "drop in hormones." In practice, what occurs is a profound disruption of the hypothalamic-pituitary-ovarian axis, with unpredictable fluctuations in FSH and estradiol, which explain both the symptoms and the famous "hormonal peaks." It is precisely here that the great clinical question arises: if estradiol peaks already exist, does it make sense to prescribe estradiol? In this video, I delve deeper into this reasoning based on physiology, explaining why, in many cases, the appropriate use of estradiol does not worsen—and may, in fact, reorganize—this system.