Comparing the Second Generation Hormone Therapies | Ask a Prostate Expert, Mark Scholz, MD

As of early 2021, the FDA has approved four second-generation anti-androgen mediations: Zytiga (abiraterone acetate), Xtandi (enzalutamide), Erleada (apalutamide), and Nubeqa (darolutamide). Here, Alex asks medical oncologist Mark Scholz, MD, how these medications work and how they compare to one another, especially regarding side effects. 0:05 How exactly do second-generation anti-androgens treat metastatic lesions? 1:33 What are the possible side effects of the four second-generation anti-androgens? How do they compare? 3:06 Are any of the four second-generation anti-androgens more appropriate than the others for men with heart problems? 3:56 What are some ways to mitigate the side effects of second-generation anti-androgen medications? 5:01 How do second-generation hormone therapies tend to affect PSA? Don’t know your stage? Take the quiz: Visit http://www.prostatecancerstaging.org To learn more about prostate cancer visit http://www.pcri.org Who we are: The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians, for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website or call our free helpline at 1 (800) 641-7274 with any questions that you have. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors. The information on the Prostate Cancer Research Institute's YouTube channel is provided with the understanding that the Institute is not engaged in rendering medical advice or recommendation. The information provided in these videos should not replace consultations with qualified health care professionals to meet your individual medical needs. #ProstateCancer #Prostate #MarkScholzMD