The Science of Energizing Weed: THCV, Terpenes, and Cannabis Genetics

Is energizing cannabis real—or is it a myth? In this episode of Senior Savvy Cannabis, I’m joined by Dr. Alisha Holloway, Chief Science Officer at Phylos, to break down the actual science behind energizing weed—and why THCV may be the cannabinoid that changes everything. We explore how cannabis genetics shape effects, why most modern dispensary cannabis makes people feel tired or foggy, and how scientists are now breeding plants specifically for energy, focus, appetite control, and motivation—not couch lock. Dr. Holloway explains: What a cannabis geneticist actually does Why THCV behaves differently than THC and CBD in the body How tiny genetic changes can dramatically alter cannabis effects The role of terpenes like terpinolene—and why myrcene dominance is a problem How Phylos bred cannabis with high THCV and controlled THC What clinical trials reveal about energy, fatigue, appetite, and focus Why “energizing weed” isn’t marketing—it’s genetics If you’ve ever said “weed used to feel different” or wondered why cannabis makes you tired when you want to feel clear, motivated, and engaged with life—this conversation is for you. This episode is part of my ongoing mission to show a different side of cannabis: one that supports intentional living, wellness, and participation in your life, not zoning out. Subscribe for science-backed cannabis education designed for grown-ups who want cannabis that works with their body—not against it. 00:00 – Is energizing cannabis real or a myth? 01:05 – Meet Dr. Alisha Holloway, Chief Science Officer at Phylos 02:15 – What does a cannabis geneticist actually do? 04:30 – Fun facts about the cannabis genome (X & Y chromosomes) 06:45 – Why modern weed makes so many people tired 08:20 – THCV explained: how it differs from THC and CBD 11:10 – How a tiny molecular change creates energizing effects 13:40 – How Phylos breeds high-THCV cannabis 16:30 – THC + THCV ratios and why balance matters 18:10 – Terpenes, terpinolene, and the myrcene problem 20:30 – Clinical trials: THCV, appetite, fatigue, and focus 23:10 – Why energizing cannabis isn’t a myth 24:20 – Final thoughts on the future of cannabis genetics