Lecture1 - MI210: Essentials of Population PK-PD Modeling and Simulation (2010)

Course materials available for download here: https://www.metrumrg.com/courses/ These training resources are provided by Metrum Institute at no cost. Course materials are licensed under Creative Commons Attribution 3 (http://creativecommons.org/licenses/b.... Additional technical consulting and custom training options are available separately, from Metrum Research Group (http://metrumrg.com). MI210 provides an extensive overview of topics in population pharmacokinetics and pharmacodynamics, including nonlinear mixed-effects modeling theory and implementation, data formatting requirements, population model development, model evaluation techniques, continuous PK-PD models, Monte Carlo simulation, and best practices. Instruction combines didactic lectures with hands-on exercises using R, MIfuns, and the NONMEM® 7 software.