AI is Changing Wearables in 2026(?) and Predicts 130 Diseases from Sleep! (Episode 8)

📝Summary In this episode, biological data scientists Rob and Stephan critically assess the current use of AI in the wearable market, ranging from the practical limitations of Oura and Whoop coaches to the potential of Google’s Gemini and Withings’ biomarker-tracking devices. The central scientific discussion focuses on "SleepFM," a groundbreaking foundation model published in Nature Medicine that utilizes self-supervised learning on polysomnography data to predict over 130 diseases, biological age, and mortality risk from a single night of sleep with unprecedented accuracy. We speculate on how this technology could bridge the gap between clinical sleep labs and consumer wearables, potentially transforming preventive medicine through longitudinal tracking and non-invasive sensors. ⏳Chapters 00:00:00 AI in wearables and their current capabilities 00:01:21 AI Coaches: Testing the limits of Oura, Whoop, and Garmin 00:12:24 The Smart Toilet: Withings U-Scan and the value of waste biomarkers 00:23:00 Environmental Health: PVC off-gassing and vinyl records 00:28:15 Generative AI: ChatGPT Health and Claude for Life Sciences 00:37:17 SleepFM: A multimodal sleep foundation model for disease prediction 00:43:00 Self-Supervised Learning: How foundation models learn from sleep data 00:51:00 Disease Prediction: Predicting 130 conditions with unseen accuracy 00:59:46 The Future: Translating clinical models to consumer wearables 01:19:25 Community Feedback 📚Resources (short version) [Introducing Oura Advisor](https://ouraring.com/blog/oura-advisor/) [WHOOP Coach Powered by OpenAI](https://www.whoop.com/at/en/thelocker...) [Active Intelligence With Garmin Connect+](https://support.garmin.com/en-US/?faq...) [U-Scan Nutrio](https://www.withings.com/us/en/u-scan...) News: Withings latest smart scale (‘longevity station’) [Withings Intelligence](https://media.withings.com/press/pres...) [Ketone bodies](https://en.wikipedia.org/wiki/Ketone_...) [Ketosis: Definition, Benefits & Side Effects](https://my.clevelandclinic.org/health...) [Air Quality Measurement Device](https://www.netatmo.com/en-eu/smart-i...) [VINYL: Maybe it's time we had an intervention.](   • VINYL: Maybe it's time we had an intervent...  ) [Introducing ChatGPT Health](https://openai.com/index/introducing-...) [Segment about AI in health(care)](https://info.deeplearning.ai/governme...) [Claude in healthcare and the life sciences](https://www.anthropic.com/news/health...) [Healthcare Spending \- Our World in Data](https://ourworldindata.org/financing-...) [Swarm Learning](https://www.nature.com/articles/s4158...) [SleepFM \- Nature Medicine paper](https://www.nature.com/articles/s4159...) [Stanford Sleep Bench v1.0](https://bdsp.io/content/08vg8vqv2wdtw...) [Foundation model](https://en.wikipedia.org/wiki/Foundat...) [Self-supervised learning](https://en.wikipedia.org/wiki/Self-su...) [ImageNet](https://en.wikipedia.org/wiki/ImageNet) [Fine-tuning](https://en.wikipedia.org/wiki/Fine-tu...\(deep_learning\)) [Reinforcement learning from human feedback](https://en.wikipedia.org/wiki/Reinfor...) (RLHF) C-index: [Evaluating Survival Models](https://scikit-survival.readthedocs.i...) [Best Wearables for Sleep: Scientific Rankings](   • Best Wearables for Sleep: Scientific Rankings  ) (2025-10) [Philips Somnolyzer 24x7 for automated sleep staging](https://www.documents.philips.com/ass...) [AUROC of blood pressure to predict ASCVD \~0.80](https://pmc.ncbi.nlm.nih.gov/articles...) [Atorvastatin](https://en.wikipedia.org/wiki/Atorvas...) (Lipitor) Life expectancy: Netherlands (82.2) vs Austria (82.0) [Diagnostic and Statistical Manual of Mental Illnesses (DSM-5)] Mechanism does not imply outcome. Outcome implies mechanism. \- Layne Norton [No Biological Free Lunches](https://tim.blog/2024/02/02/no-biolog...) 🎙️Other Platforms [Learn more](https://www.fitforscience.com/) and subscribe on your favorite platforms: [YouTube](   / @fitforscience  ) [Spotify](https://open.spotify.com/show/56TjUxu...) [Apple Podcasts](https://podcasts.apple.com/us/podcast...) [Amazon Music](https://music.amazon.de/podcasts/c3e5...) ⚠️Disclaimer: This podcast represents our own opinions and is for informational purposes only. It does not constitute medical or financial advice or a professional relationship.