S5E8 - Anti Xa and UFH monitoring

Presented by Lisa Gannon & Anne-Cécile Ortega // Special guest: Dr. Isabelle Gouin-Thibault, Medical Pathologist and the Head of the Hemostasis Department at the University Hospital of Rennes (France). Welcome to Ask Stago, the podcast dedicated to provide expert answers to your expert questions in coagulation.  In today’s episode, our guest Doctor Isabelle Gouin-Thibault will discuss the influence of dextran sulfate in anti-Xa assay.  Literature sources:  Lasne, D. et al. (2023) Factors Influencing Anti-Xa Assays: A Multicenter Prospective Study in Critically Ill and Noncritically Ill Patients Receiving Unfractionated Heparin. Thrombosis and Haemostasis, 123 (12), 1105.  Hardy, M. et al. (2023) Reassessment of dextran sulfate in anti-Xa assay for unfractionated heparin laboratory monitoring. Res Pract Thromb Haemost. 7 (8), 102257  Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.